Journal of Spine Practice

ISSN: 2789-9462

Leading research in all spine subspecialties focusing on orthopaedic spine, neurosurgery, radiology, and pain management.

Regional anesthesia in spine surgery: A narrative review

Published date: Jul 04 2023

Journal Title: Journal of Spine Practice

Issue title: Journal of Spine Practice (JSP): Volume 2, Issue 2

Pages: 40-50

DOI: 10.18502/jsp.v2i2.13223

Authors:

David Salven - david.salven@duke.edu - https://orcid.org/0000-0002-5618-3446

David Sykes - david.sykes@duke.edu

Melissa Erickson - melissa.erickson@duke.edu

Khoi Than - khoi.than@duke.edu

Peter Grossi - peter.grossi@duke.edu

Clifford Crutcher - clifford.crutcher@duke.edu

Miles Berger - miles.berger@duke.edu

W. Michael Bullock - william.bullock@duke.edu

Jeff Gadsden - jeff.gadsden@duke.edu

Muhammad Abd-El-Barr - m.abdelbarr@duke.edu

Abstract:

Background: Regional anesthesia, which refers to the use of anesthetics to provide analgesia to a specific body part or nervous innervation territory, has become increasingly popular in the field of spine surgery. With the application of these techniques, it has been postulated that patients will require less systemic analgesia, intraoperatively and postoperatively. The authors of this narrative review discuss the common regional anesthetic modalities applied to spine surgery, in addition to patient selection criteria, success in patients with multiple comorbid illnesses, and its adoption by surgeons.

Materials and Methods: An advanced search was performed in the PubMed database to obtain Englishlanguage articles discussing regional anesthesia, awake spine surgery, and postoperative complications. Articles were screened for relevance, and 47 articles were incorporated into this narrative review.

Results: Classic neuraxial and paraspinal techniques have allowed surgeons to perform posterior decompression, fusion, and revision procedures. Transversus abdominus plane and quadratus lumborum blocks have enabled better pain control in patients undergoing surgeries requiring anterior or lateral approaches. Documented benefits of regional anesthesia include shorter operative time, improved pain control and hemodynamic stability, as well as decreased cost and length of stay. Several case series have demonstrated the success of these techniques in highly comorbid patients.

Conclusion: Regional anesthesia provides an exciting opportunity to make surgical treatment possible for spine patients with significant comorbidities. Although additional randomized controlled trials are necessary to further refine patient selection criteria, current data demonstrates its safety and efficacy in the operating room.

References:

[1] Garg B, Ahuja K, Sharan AD. Regional anesthesia for spine surgery. J Am Acad Orthop Surg 2022; 30(17): 809–819.

[2] Meng T, Zhong Z, Meng L. Impact of spinal anaesthesia vs. general anaesthesia on peri-operative outcome in lumbar spine surgery: A systematic review and meta-analysis of randomised, controlled trials. Anaesthesia 2017; 72(3): 391–401.

[3] Zorrilla-Vaca A, Healy RJ, Mirski MA. A comparison of regional versus general anesthesia for lumbar spine surgery: A meta-analysis of randomized studies. J Neurosurg Anesthesiol 2017; 29(4): 415–425.

[4] Butler AJ, Brusko GD, Wang MY. Awake endoscopic transforaminal lumbar interbody fusion: A technical note. HSS J 2020; 16(2): 200–204.

[5] Fiani B, Reardon T, Selvage J, Dahan A, El-Farra MH, Endres P, et al. Awake spine surgery: An eye-opening movement. Surg Neurol Int 2021; 12: 222.

[6] Cook TM. Combined spinal-epidural techniques. Anaesthesia 2000; 55(1): 42–64.

[7] Wu K, Zhao Y, Feng Z, Hu X, Chen Z, Wang Y. Stepwise local anesthesia for percutaneous endoscopic interlaminar discectomy: Technique strategy and clinical outcomes. World Neurosurg 2020; 134: e346–e52.

[8] Kraiwattanapong C, Arnuntasupakul V, Kantawan R, Woratanarat P, Keorochana G, Langsanam N. Effect of multimodal drugs infiltration on postoperative pain in split laminectomy of lumbar spine: A randomized controlled trial. Spine 2020; 45(24): 1687–1695.

[9] Braxton EE, Brena KR, Spears H, Conrad E, Heinze JD. Ultrasound-guided bilateral erector spinae plane nerve blocks: A novel application for the management of acute postoperative pain in awake spine surgery. Illustrative case. J Neurosurg Case Lessons 2022; 3(18).

[10] Kanna RM, Ramachandran K, Subramanian JB, Shetty AP, Rajasekaran S. Perioperative analgesic efficacy and safety of erector spinae plane block in posterior cervical spine surgery-a double blinded, randomized controlled study. Spine J 2023; 23(1): 6–13.

[11] Zhu L, Wang M, Wang X, Wang Y, Chen L, Li J. Changes of opioid consumption after lumbar fusion using ultrasoundguided lumbar erector spinae plane block: A randomized controlled trial. Pain Physician 2021; 24(2): E161–E168.

[12] Singh S, Choudhary NK, Lalin D, Verma VK. Bilateral ultrasound-guided erector spinae plane block for postoperative analgesia in lumbar spine surgery: A randomized control trial. J Neurosurg Anesthesiol 2020; 32(4): 330–334.

[13] van den Broek RJC, van de Geer R, Schepel NC, Liu WY, Bouwman RA, Versyck B. Evaluation of adding the Erector spinae plane block to standard anesthetic care in patients undergoing posterior lumbar interbody fusion surgery. Sci Rep 2021; 11(1): 7631.

[14] Yu Y, Wang M, Ying H, Ding J, Wang H, Wang Y. The analgesic efficacy of erector spinae plane blocks in patients undergoing posterior lumbar spinal surgery for lumbar fracture. World Neurosurg 2021; 147: e1–e7.

[15] Cirenei C, Boussemart P, Leroy HA, Assaker R, Tavernier B. Effectiveness of bilateral ultrasound-guided erector spinae plane block in percutaneous lumbar osteosynthesis for spine trauma: A retrospective study. World Neurosurg 2021; 150: e585–e590.

[16] Finnerty D, Ni Eochagain A, Ahmed M, Poynton A, Butler JS, Buggy DJ. A randomised trial of bilateral erector spinae plane block vs. no block for thoracolumbar decompressive spinal surgery. Anaesthesia 2021; 76(11): 1499–1503.

[17] Ye Y, Bi Y, Ma J, Liu B. Thoracolumbar interfascial plane block for postoperative analgesia in spine surgery: A systematic review and meta-analysis. PLoS One 2021; 16(5): e0251980.

[18] Ekinci M, Ciftci B, Celik EC, Yayik AM, Tahta A, Atalay YO. A comparison of the ultrasound-guided modified thoracolumbar interfascial plane block and wound infiltration for postoperative pain management in lumbar spinal surgery patients. Agri 2020; 32(3): 140–146.

[19] Morgenstern C, Ramirez-Paesano C, Juanola Galceran A, Morgenstern R. Thoracolumbar interfascial plane block results in opioid-free postoperative recovery after percutaneous/endoscopic transforaminal lumbar interbody fusion surgery. World Neurosurg 2021; 153: e473–e480.

[20] Ciftci B, Ekinci M, Celik EC, Yayik AM, Aydin ME, Ahiskalioglu A. Ultrasound-guided erector spinae plane block versus modified-thoracolumbar interfascial plane block for lumbar discectomy surgery: A randomized, controlled study. World Neurosurg 2020; 144: e849–e855.

[21] Reisener MJ, Hughes AP, Okano I, Zhu J, Lu S, Salzmann SN, et al. The association of transversus abdominis plane block with length of stay, pain and opioid consumption after anterior or lateral lumbar fusion: A retrospective study. Eur Spine J 2021; 30(12): 3738–3745.

[22] Elsharkawy H, El-Boghdadly K, Barrington M. Quadratus lumborum block: Anatomical concepts, mechanisms, and techniques. Anesthesiology 2019; 130(2): 322–335.

[23] Huda AU, Minhas R. Quadratus lumborum block reduces postoperative pain scores and opioids consumption in total hip arthroplasty: A meta-analysis. Cureus 2022; 14(2): e22287.

[24] Wilton J, Chiu H, Codianne N, Knapp H, Escolar VR, Burns S. Continuous quadratus lumborum block as postoperative strategy for pain control in spinal fusion surgery. Indian J Anaesth 2020; 64(10): 869–873.

[25] Letchuman V, Agarwal N, Mummaneni VP, Wang MY, Shabani S, Patel A, et al. Awake spinal surgery: Simplifying the learning curve with a patient selection algorithm. Neurosurg Focus 2021; 51(6): E2.


[26] Breton JM, Ludwig CG, Yang MJ, Nail TJ, Riesenburger RI, Liu P, et al. Spinal anesthesia in contemporary and complex lumbar spine surgery: Experience with 343 cases. J Neurosurg Spine 2022; 36(4): 534–541.

[27] Urick D, Sciavolino B, Wang TY, Gupta DK, Sharan A, Abd-El-Barr MM. Perioperative outcomes of general versus spinal anesthesia in the lumbar spine surgery population: A systematic review and meta-analysis of data from 2005 through 2021. J Clin Orthop Trauma 2022; 30: 101923.

[28] Khattab MFM, Sykes DAW, Abd-El-Barr MM, Waguia R, Montaser A, Ghamry SE, et al. Spine surgery under awake spinal anesthesia: An Egyptian experience during the COVID-19 pandemic. Neurosurg Focus 2021; 51(6): E6.

[29] Schulte PJ, Roberts RO, Knopman DS, Petersen RC, Hanson AC, Schroeder DR, et al. Association between exposure to anaesthesia and surgery and long-term cognitive trajectories in older adults: Report from the Mayo Clinic Study of Aging. Br J Anaesth 2018; 121(2): 398–405.

[30] Zhang LM, Hornor MA, Robinson T, Rosenthal RA, Ko CY, Russell MM. Evaluation of postoperative functional health status decline among older adults. JAMA Surg 2020; 155(10): 950–958.

[31] Telfeian AE, Oyelese A, Fridley J, Doberstein C, Gokaslan ZL. Endoscopic surgical treatment for symptomatic spinal metastases in long-term cancer survivors. J Spine Surg 2020; 6(2): 372–382.

[32] De Biase G, Gruenbaum SE, West JL, Chen S, Bojaxhi E, Kryzanski J, et al. Spinal versus general anesthesia for minimally invasive transforaminal lumbar interbody fusion: Implications on operating room time, pain, and ambulation. Neurosurg Focus 2021; 51(6): E3.

[33] Abode-Iyamah K, Ghaith AK, Bhandarkar AR, De Biase G, Rajjoub R, Chen SG, et al. Single-level awake transforaminal lumbar interbody fusion: A Mayo Clinic institutional experience and national analysis. Neurosurg Focus 2021; 51(6): E4.

[34] Perez-Roman RJ, Govindarajan V, Bryant JP, Wang MY. Spinal anesthesia in awake surgical procedures of the lumbar spine: A systematic review and meta-analysis of 3709 patients. Neurosurg Focus 2021; 51(6): E7.

[35] Telfeian AE, Sastry R, Oyelese A, Fridley J, Camara- Quintana JQ, Niu T, et al. Awake, transforaminal endoscopic lumbar spine surgery in octogenarians: Case series. Pain Physician 2022; 25(2): E255–E262.

[36] Telfeian AE, Moldovan K, Shaaya E, Syed S, Oyelese A, Fridley J, et al. Awake, endoscopic revision surgery for lumbar pseudarthrosis after transforaminal lumbar interbody fusion: Technical notes. World Neurosurg 2020; 136: 117–121.

[37] Hagan MJ, Telfeian AE, Sastry R, Ali R, Lewandrowski KU, Konakondla S, et al. Awake transforaminal endoscopic lumbar facet cyst resection: Technical note and case series. J Neurosurg Spine 2022; 37(6): 843–850.

[38] Ahern DP, Gibbons D, Johnson GP, Murphy TM, Schroeder GD, Vaccaro AR, et al. Management of herniated lumbar disk disease and cauda equina syndrome in pregnancy. Clin Spine Surg 2019; 32(10): 412–416.

[39] Vasco Ramirez M, Valencia GC. Anesthesia for nonobstetric surgery in pregnancy. Clin Obstet Gynecol 2020; 63(2): 351–363.

[40] Babici D, Johansen PM, Newman SL, O’Connor TE, Miller TD. Microdiscectomy under local anesthesia and spinal block in a pregnant female. Cureus 2021; 13(12): e20241.

[41] De Biase G, Bechtle P, Leone B, Quinones-Hinojosa A, Abode-Iyamah K. Awake minimally invasive transforaminal lumbar interbody fusion with a pediclebased retraction system. Clin Neurol Neurosurg 2021; 200: 106313.

[42] Garg B, Ahuja K, Sharan AD. Awake spinal fusion. J Clin Orthop Trauma 2020; 11(5): 749–752.

[43] Chan AK, Gnaedinger A, Ayoub C, Gupta DK, Abd-El- Barr MM. The ”In-Parallel” technique for awake, bilateral simultaneous minimally invasive transforaminal lumbar interbody fusion and multilevel lumbar decompression. Oper Neurosurg 2023; 24(3): e160–e169.

[44] Azad TD, Alomari S, Khalifeh JM, Ahmed AK, Musharbash FN, Mo K, et al. Adoption of awake spine surgery - Trends from a national registry over 14 years. Spine J 2022; 22(10): 1601–1609.

[45] De Biase G, Carter RE, Otamendi-Lopez A, Garcia D, Chen S, Bojaxhi E, et al. Assessment of surgeons’ attitude towards awake spine surgery under spinal anesthesia. J Clin Neurosci 2023; 107: 48–53.

[46] De Biase G, Chen S, Ziu E, Garcia D, Bojaxhi E, Carter RE, et al. Assessment of patients’ willingness to participate in a randomized trial of spinal versus general anesthesia for lumbar spine surgery. World Neurosurg 2022; 161: e635– e641.

[47] West JL, De Biase G, Bydon M, Bojaxhi E, Mendhi M, Quinones-Hinojosa A, et al. What is the learning curve for lumbar spine surgery under spinal anesthesia? World Neurosurg 2022; 158: e310–e316.

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