Journal of Ophthalmic and Vision Research

Published date: Sep 09 2025

Journal Title: Journal of Ophthalmic and Vision Research

Issue title: ‎Volume 20 - 2025

Pages: 1 - 4

DOI: 10.18502/jovr.v20.15749

Arthur Hammera.hammer@nhs.netMoorfields Eye Hospital, NHS Foundation Trust, London

Ammatul Takazaammatul.takaza@nhs.netSt George’s, University of London, London

Mark Lanemark.lane7@nhs.netMoorfields Eye Hospital, NHS Foundation Trust, London

Azizur RahmanMoorfields Eye Hospital, NHS Foundation Trust, London

Alfonso Vasquez-Perezalest99@gmail.comMoorfields Eye Hospital, NHS Foundation Trust, London

Purpose: To present our experience with patients who developed donor-implanted guttata (DIG) following uncomplicated corneal endothelial transplantation.

Case Report: Three patients who underwent Descemet membrane endothelial keratoplasty were diagnosed with DIG, which was confirmed by confocal microscopy. Two of the cases received corneas from the same donor and experienced delayed recovery of corneal transparency despite fully attached grafts.

Conclusion: Fuchs endothelial dystrophy is a common condition within the general population and is likely to be present in donor corneas. We assessed three cases of DIG, and the results highlight the need for improved screening of this condition prior to transplantation and its consideration in the early postoperative period if corneal edema is present despite graft attachment.

Keywords: Descemet Membrane Endothelial Keratoplasty, Donor Implanted Guttata, Eye Bank Screening, Fuchs Endothelial Dystrophy, Penetrating Keratoplasty

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