West Kazakhstan Medical Journal

Published date: Jun 02 2025

Journal Title: West Kazakhstan Medical Journal

Issue title: West Kazakhstan Medical Journal: Volume 67 Issue 2

Pages: 198 - 207

DOI: 10.18502/wkmj.v67i2.17191

Gani Kuttymuratovaiger2000@mail.ruDepartment of General Surgery, University Medical Center, Astana

Ardak AinakulovArdak.Ainakulov@umc.org.kzDepartment of Urology and Kidney Transplantation, University Medical Center, Astana

Askar Ayaganovaskar_kaz@mail.ruDepartment of Anesthesiology, Resuscitation and Intensive Care, University Medical Center, Astana

Zhanat Komekbayzhanat.ru@inbox.ruDepartment of Histology, West Kazakhstan Medical University named Ospanov Marat, Aktobe city

Aizada Sarinaaizada_sarina@mail.ruDepartment of Histology, West Kazakhstan Medical University named Ospanov Marat, Aktobe city

Zhandos Imanberdiyevzhandos.Imanberdiyev@umc.org.kzDepartment of Urology and Kidney Transplantation, University Medical Center, Astana

Bahitzhan Abdimazhitovbakhitzhan.abdimazhitov@umc.org.kzDepartment of Urology and Kidney Transplantation, University Medical Center, Astana

Tuleuzhan Abdurakhmanabilek_akt@mail.ruDepartment of General Surgery, West Kazakhstan Medical University named Ospanov Marat, Aktobe city

Fariza EskaraYesara01@mail.ruDepartment of Histology, West Kazakhstan Medical University named Ospanov Marat, Aktobe city

Alisher Garifollinalisherg97@gmail.comDepartment of Histology, West Kazakhstan Medical University named Ospanov Marat, Aktobe city

Zhandos Kadyrovkadyrov.zhandos@mail.ruDepartment of General Surgery, West Kazakhstan Medical University named Ospanov Marat, Aktobe city

This study presents a histological analysis of a transplanted donor kidney, including its ureter, a part of the contralateral ureter, and a segment of the bladder, enbloc transplanted into recipients with simulated microcystis in a porcine model. The experiment was carried out on six pigs, three donors and three recipients, under general intubation anesthesia. From each donor, the left kidney with the ureter and a triangular bladder segment with the right ureter were removed as a single block and perfused with an organ preservation solution. In recipients, the right kidney with ureter, apex of the bladder, and left ureter were removed. Orthotopic organ transplantation was performed. Donors were euthanized post-surgery, while recipients were observed for 7 days. Subsequently, the recipients underwent relaparotomy, visual assessment, and histological examination. Histological analysis of transplanted organs reveals the presence of blood supply to the graft tissues, especially the part of the donor bladder. This indicates a high probability of good organ engraftment. This study focuses on evaluating graft vascularization, with long-term engraftment being addressed in future research.

Keywords: kidney transplant, ureteral transplant, transplantation of part of the bladder, histology, microcystis

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