West Kazakhstan Medical Journal

Published date: Jun 02 2025

Journal Title: West Kazakhstan Medical Journal

Issue title: West Kazakhstan Medical Journal: Volume 67 Issue 2

Pages: 238 - 246

DOI: 10.18502/wkmj.v67i2.17123

Ainur Amanzholkyzya.ainur.82@mail.ruDepartment of Normal Physiology, Faculty of General Medicine, Non-Commercial joint-stock Society, West Kazakhstan Marat Ospanov Medical University, Aktobe

Samat Saparbayevsamat-saparbayev@mail.ruMedical doctors for Scientific and Clinical Work at Al-Jami, Astana

Roza Nurgaliyevanuroz61@mail.ruDepartment of Normal Physiology, Faculty of General Medicine, Non-Commercial joint-stock Society, West Kazakhstan Marat Ospanov Medical University, Aktobe

Ainur DonayevaAinurzhan_ed@mail.ruDepartment of Normal Physiology, Faculty of General Medicine, Non-Commercial joint-stock Society, West Kazakhstan Marat Ospanov Medical University, Aktobe

Gulnara Gubashevagulnara.k@mail.ruDepartment of Obstetrics and Gynecology №2, Faculty of General Medicine, Non-Commercial Joint-stock Society, West Kazakhstan Marat Ospanov Medical University, Aktobe

Raisa Aringazinaraisa_aringazina@mail.ruDepartment of Internal Diseases № 1, Faculty of General Medicine, Non-Commercial Joint-stock Society, West Kazakhstan Marat Ospanov Medical University, Aktobe

TThis study aimed to identify lipid metabolism features in young smokers, specifically in students from the West Kazakhstan Marat Ospanov Medical University. A comprehensive clinical and instrumental examination of 154 male students was conducted. Depending on the smoking status, the subjects were divided into two groups (group one – non-smokers, n=95, group two – smokers, n=59). Lipid profile was studied and atherogenicity coefficient was calculated to assess the state of vascular endothelium. Blood pressure above reference values was recorded in 1.1% of subjects in the first group and 3.4% in the second group. Obesity was found in 10.5% of students in group one and 11.9% in group two. The level of total cholesterol in group one was increased to 3.2% and 1.7% in group two. Increased level of triglycerides was detected in both groups at 9.5% and 6.8%, respectively. It was found that lowdensity lipoprotein (LDL) levels were higher than normal in group one, and high-density lipoprotein levels were lower in both groups. The atherogenic coefficient increased by 11.6% in the first group and 13.6% in the second. The study results indicate the presence of risk factors for the development of cardiovascular pathology in students, particularly through alterations in lipid balance.

Keywords: smoking, metabolism, lipid metabolism, total cholesterol, low-density lipoproteins, high-density lipoproteins

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