West Kazakhstan Medical Journal

ISSN: 2707-6180 (Print) 2707-6199 (Online)

Pioneering research advancing the frontiers of medical knowledge and healthcare practices.

Crimean-Congo Hemorrhagic Fever in the Zhambyl Region: Epidemiological Features of the Occurrence of Infection in 2023

Published date:Sep 26 2024

Journal Title: West Kazakhstan Medical Journal

Issue title: West Kazakhstan Medical Journal: Volume 66 Issue 3

Pages:302 - 311

DOI: 10.18502/wkmj.v66i3.16571

Authors:

Talgat I. Nurmakhanovnti72@mail.ruM.Aikimbaev’s National Scientific Center for Especially Dangerous Infections, Ministry of Health Republic of Kazakhstan, Almaty

Nur B. TukhanovaM.Aikimbaev’s National Scientific Center for Especially Dangerous Infections, Ministry of Health Republic of Kazakhstan, Almaty

Nurkeldi A. TurebekovM.Aikimbaev’s National Scientific Center for Especially Dangerous Infections, Ministry of Health Republic of Kazakhstan, Almaty

Anna L. ShinM.Aikimbaev’s National Scientific Center for Especially Dangerous Infections, Ministry of Health Republic of Kazakhstan, Almaty

Zauresh B. ZhumadilovaM.Aikimbaev’s National Scientific Center for Especially Dangerous Infections, Ministry of Health Republic of Kazakhstan, Almaty

Gulnara Zh. TokmurziyevaM.Aikimbaev’s National Scientific Center for Especially Dangerous Infections, Ministry of Health Republic of Kazakhstan, Almaty

Baydilda S. ShinaliyevDepartment of Sanitary and Epidemiological Control of Zhambyl Region, Committee of Sanitary- Epidemiological Control, Ministry of Health Republic of Kazakhstan, Taraz

Neili O. MulikovaDepartment of Sanitary and Epidemiological Control of Zhambyl Region, Committee of Sanitary- Epidemiological Control, Ministry of Health Republic of Kazakhstan, Taraz

Abstract:

Crimean-Congo hemorrhagic fever (CCHF) is an acute tick-borne viral infection with a high fatality rate. The main vector of the CCHF virus is ticks of the genus Hyalomma. Humans get infected through tick bites or by direct contact with the blood of infected humans or domestic animals. The endemic regions of CCHF in Kazakhstan are Kyzylorda, Turkestan, and Zhambyl. In the Zhambyl region, the first evidence of human cases was reported in 1982. In the following years, cases of CCHF were annually registered in two districts (Sarysu and Moiynkum) of the Zhambyl region. The study goal is twofold: 1) to provide a retrospective review of CCHF cases reported through the surveillance system in the Zhambyl region from 1991 to 2023 and 2) to analyze epidemiological features of CCHF cases in the Zhambyl region in 2023. Surveillance data on CCHF during the 1991–2023 period in the Zhambyl region were extracted from the “Report on selected infectious and parasitic diseases”. Incidence (per 100,000 population) was defined as the number of annual new cases divided by the total population each year. Descriptive analysis was performed on case characteristics, time, and place of CCHF cases in the Zhambyl region in 2023. In total, 216 cases of CCHF were reported from 1991 to 2023. The incidence increased sharply with peak activity in 1995 and has declined since 2002. The natural foci of the disease have shifted from the Sarysu and Moiynkum districts to the Shu, Bayzak, and Zhambyl districts. Overall, 12 cases of CCHF were reported in the Zhambyl region in 2023, mainly in nonendemic (Shu, Bayzak, Zhambyl) districts. An analysis of epidemiological data for 2023 showed that the first peak of CCHF incidence was in March-June, with another peak from October to November. We observed dynamic distribution of CCHF in the Zhambyl region from 1991 to 2023, wherein Sarysu and Moiynkum endemic districts foci tended to increase by expanding to the Shu, Bayzak, Zhambyl districts. The disease trend is seasonal, and the life cycle of ticks can indirectly influence morbidity rates. Additional research is needed to elucidate the environmental, meteorological, and social factors associated with CCHF incidence in different decades.

Keywords: virus, Crimean-Congo hemorrhagic fever, tick-borne infections

References:

[1] Hawman DW, Feldmann H. Crimean-Congo haemorrhagic fever virus. Nat Rev Microbiol. 2023;21(7):463-77. doi: 10.1038/s41579-023-00871-9.

[2] Fereidouni M, Apanaskevich DA, Pecor DB, Pshenichnaya NY, Abuova GN, Tishkova FH, et al. Crimean- Congo hemorrhagic fever virus in Central, Eastern, and South-eastern Asia. Virol Sin. 2023;38(2):171-83. doi: 10.1016/j.virs.2023.01.001.

[3] Abdiyeva K, Turebekov N, Dmitrovsky A, Tukhanova N, Shin A, Yeraliyeva L, Heinrich N, Hoelscher M, Yegemberdiyeva R, Shapiyeva Z, Kachiyeva Z, Zhalmagambetova A, Montag J, Dobler G, Zinner J, Wagner E, Frey S, Essbauer S. Seroepidemiological and molecular investigations of infections with Crimean-Congo haemorrhagic fever virus in Kazakhstan. Int J Infect Dis. 2019;78:121-127. doi: 10.1016/j.ijid.2018.10.015.

[4] Abuova GN, Berdaliyeva FA, Polukchi TV, Aliyev DS, Raymkulov GS, Kulemin MV, Saylaubekuly R. Seroprevalence of Crimean-Congo hemorrhagic fever virus in the population of Turkestan region. Infez Med. 2024;32(1):83-89. doi: 10.53854/liim-3201-11.

[5] Bryant-Genevier J, Bumburidi Y, Kazazian L, Seffren V, Head JR, Berezovskiy D, Zhakipbayeva B, Salyer SJ, Knust B, Klena JD, Chiang CF, Mirzabekova G, Rakhimov K, Koekeev J, Kartabayev K, Mamadaliyev S, Guerra M, Blanton C, Shoemaker T, Singer D, Moffett DB. Prevalence of Crimean-Congo Hemorrhagic Fever Virus among Livestock and Ticks in Zhambyl Region, Kazakhstan, 2017. Am J Trop Med Hyg. 2022;106(5):1478–85. doi: 10.4269/ajtmh.21-1092.

[6] Nurmakhanov T, Sansyzbaev Y, Atshabar B, et al. Crimean-Congo haemorrhagic fever virus in Kazakhstan (1948- 2013). Int J Infect Dis. 2015;38:19-23. doi: 10.1016/j.ijid.2015.07.007.

[7] Sultankulova, K.T., Shynybekova, G.O., Kozhabergenov, N.S., Mukhami, N.N., Chervyakova, O.V., Burashev, Y.D., Zakarya, K.D., Nakhanov, A.K., Barakbayev, K.B., Orynbayev, M.B. The Prevalence and Genetic Variants of the CCHF Virus Circulating among Ticks in the Southern Regions of Kazakhstan. Pathogens 2022, 11, 841. https://doi.org/10.3390/pathogens11080841.

[8] Nurmakhanov TI, Sansyzbayev EB, Yeskhodzhayev OU, Vilkova AN, Sajlaubekuly R, Kulemin MV, et al. Genetic variants of the Crimean-Congo virus of hemorrhagic fever circulating in the territory of the South-Kazakhstan region. Medicine (Almaty). 2018;9(195):54–60. (In Russ.). doi: 10.31082/1728-452X-2018-195-3079-54-60

[9] Head JR, Bumburidi Y, Salyer SJ, Knust B, Kuralbekovna MG, Moffett DB. Prevalence of CCHF Virus in Ticks and People and Public Awareness in Zhambyl Region, Kazakhstan. Online J Public Health Inform 2018;10(1):e62282. doi: 10.5210/ojphi.v10i1.8951.

[10] Nurmakhanov T, Tukhanova N, Sayakova Z, Sadovskaya V, Shevtsov A, Tokmurziyeva G and Turebekov N Outcome of the entomological monitoring for CrimeanCongo haemorrhagic fever virus in the western and southern regions of Kazakhstan in 2021–2022. Front. Epidemiol. 2024;4:1310071. doi: 10.3389/fepid.2024.1310071.

[11] Mohammad Fereidouni, Dmitry A. Apanaskevich, David B. Pecor, Natalia Yu. Pshenichnaya, Gulzhan N. Abuova, Farida H. Tishkova, Yekaterina Bumburidi, Xiankun Zeng, Jens H. Kuhn, Maryam Keshtkar-Jahromi, Crimean- Congo hemorrhagic fever virus in Central, Eastern, and South-eastern Asia, Virologica Sinica, 2023;38(2):171-183, https://doi.org/10.1016/j.virs.2023.01.001.

[12] Tonbak S, Aktas M, Altay K, Azkur AK, Kalkan A, Bolat Y, Dumanli N, Ozdarendeli A. Crimean-Congo hemorrhagic fever virus: genetic analysis and tick survey in Turkey. J Clin Microbiol. 2006;44(11):4120-4124. doi: 10.1128/JCM.00644-06.

[13] Bente DA, Forrester NL, Watts DM, McAuley AJ, Whitehouse CA, Bray M. Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity. Antiviral Res. 2013;100(1):159-89. doi: 10.1016/j.antiviral.2013.07.006.

[14] Gray JS, Dautel H, Estrada-Peña A, Kahl O, Lindgren E. Effects of climate change on ticks and tick-borne diseases in Europe. Interdiscip Perspect Infect Dis. 2009;2009:593232. doi: 10.1155/2009/593232.

[15] Serretiello E, Astorri R, Chianese A, et al. The emerging tick-borne Crimean-Congo haemorrhagic fever virus: A narrative review. Travel Med Infect Dis. 2020;37:101871. doi: 10.1016/j.tmaid.2020.101871.

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