West Kazakhstan Medical Journal

ISSN: 2707-6180 (Print) 2707-6199 (Online)

Pioneering research advancing the frontiers of medical knowledge and healthcare practices.

Demographic Features of Ulcerative Gastroduodenal Bleeding

Published date: Jun 28 2024

Journal Title: West Kazakhstan Medical Journal

Issue title: West Kazakhstan Medical Journal: Volume 66 Issue 2

Pages: 171–175

DOI: 10.18502/wkmj.v66i2.16461

Authors:

Myltykbay Rysmakhanovtransplantaktobe@gmail.comDepartment of Surgery No2, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan

Gulmira KurmanbaiDepartment of Gastroenterology, Aktobe Medical Center, Aktobe, Kazakhstan

Anuar KoyshybayevDepartment of Surgery No2, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan

Botagoz Mukhamedgalieva Department of Surgery No2, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan

Zhanna Satenova Department of Oncology, West Kazakhstan Marat Ospanov Medical University Medical Center, Aktobe, Kazakhstan

Bazylbek ZhakiyevDepartment of Surgery No2, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan

Abstract:

Background. Gastroduodenal bleeding (GDB) is a common cause of endoscopic examinations. This study aims to study demographic criteria in patients with ulcerative genesis GDB during primary endoscopic examinations in a single center.
Materials and Methods. The diagnostic esophagogastroduodenoscopy (EGDS) of 231 patients with GDB of ulcerative etiology from January 2020 to December 2021 was analyzed, all patients were with primary EGDS. The study compared the activity of ulcerative bleeding, depending on gender and age groups.
Results. The majority of patients with ulcerative GDCS were women – 57.7%. In both groups, duodenal ulcer was the predominant cause of GDB, 61.5% in women, and 54.2% in men. Active bleeding was observed in 8 (3.4%) patients. Among all women and men, Forrest-II bleeding was detected in 126 (93.4%) and 86 (89.6%) patients, respectively. In women and men, GDB is most common over the age of 50 (83.7% and 59.3%). Significant differences were observed, such as GDB occurs more often in men at the age of 41–50 years, whereas in women it occurs more often at the age of 51–60 years (p < 0.05). Bleeding activity according to Forrest did not depend on gender (p > 0.05).
Conclusion. The risk of bleeding among both women and men is higher over the age of 50. At the same time, the activity of GDK does not depend on the gender and age of the patient.

Keywords: gastroduodenal bleeding, ulcer bleeding, bleeding epidemiology

References:

[1] Gralnek IM, Stanley AJ, Morris AJ, Camus M, Lau J, Lanas A, et al. Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2021. Endoscopy. 2021 Mar;53(3):300–332.

[2] Darzi AJ, Karam SG, Charide R, Etxeandia- Ikobaltzeta I, Cushman M, Gould MK, et al. Prognostic factors for VTE and bleeding in hospitalized medical patients: A systematic review and metaanalysis. Blood. 2020 May;135(20):1788–1810.

[3] Ferroni E, Denas G, Gennaro N, Fedeli U, Pengo V. Gender related differences in gastrointestinal bleeding with oral anticoagulation in atrial fibrillation. J Cardiovasc Pharmacol Ther. 2022;27:10742484211054609.

[4] Kate V, Sureshkumar S, Gurushankari B, Kalayarasan R. Acute upper non-variceal and lower gastrointestinal bleeding. J Gastrointest Surg. 2022 Apr;26(4):932–949.

[5] Arai J, Kato J, Toda N, Kurokawa K, Shibata C, Kurosaki S, et al. Risk factors of poor prognosis and impairment of activities of daily living in patients with hemorrhagic gastroduodenal ulcers. BMC Gastroenterol. 2021 Jan;21(1):16.

[6] Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointestinal bleeding. Lancet. 1974 Aug;2(7877):394–397.

[7] Ruiz J, López-Vinardell L, Juanes A, Riera-Magallon A, Puig M, Mangues MA. Risk factors for emergency department revisit in elderly patients with gastrointestinal bleeding secondary to anticoagulant therapy. Eur J Hosp Pharm Sci Pract. 2022 Sep;29(5):271–274.

[8] Kisuule I, Seremba E, Kagimu M. Prevalence of gastrointestinal bleeding and frequency of selected predictors of mortality on the medical emergency ward at Mulago hospital. Afr Health Sci. 2023 Mar;23(1):622–630.

[9] Kamada T, Satoh K, Itoh T, Ito M, Iwamoto J, Okimoto T, et al. Evidence-based clinical practice guidelines for peptic ulcer disease 2020. J Gastroenterol. 2021 Apr;56(4):303–322.

[10] Wilkins T, Wheeler B, Carpenter M. Upper gastrointestinal bleeding in adults: Evaluation and management [Erratum in: Am Fam Physician. 2021 Jan 15;103] [2] [:70. PMID: 32109037]. Am Fam Physician. 2020 Mar;101(5):294–300.

[11] Liao F, Yang Y, Zhong J, Zhu Z, Pan X, Liao W, et al. Incidence and risk factors for rebleeding after emergency endoscopic hemostasis for marginal ulcer bleeding. Clin Res Hepatol Gastroenterol. 2022 Oct;46(8):101953.

Download
HTML
Cite
Share
statistics

161 Abstract Views

74 PDF Downloads