Published date: Mar 31 2020

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 15 (2020), Issue No. 1

Pages: 56-64

DOI: 10.18502/sjms.v15i1.6705

A MolanaeiDepartment of Internal Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran

SA SeyedoshohadaeiDepartment of Psychiatry, Kurdistan University of Medical Sciences, Sanandaj, Iran

S HasaniS.hasani@muk.ac.irDepartment of Microbiology Sciences, Islamic Azad University, Sanandaj Branch, Sanandaj, Iran

P SharifiDepartment of Microbiology Sciences, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran

M RashidianDepartment of Microbiology Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran

A TaherpourDepartment of Microbiology Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran

S TozandehJaniDepartment of Biology, Faculty of Sciences, University of Kurdistan, Sanandaj, Iran

S HasaniLung Diseases and Allergy Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran

Introduction: Bacterial resistance to antibacterial agents is a very serious threat to public health. Where some antibacterial agents prove ineffective, the antibacterial properties of honey have been shown to be highly efficacious against several human bacterial pathogens. The purpose of this study is to investigate the sensitivity of Staphylococcus aureus isolated from the nursing staff of a hospital to natural honey.

Methods: In this study, 35 strains of methicillin-resistant S. aurous samples were selected from hospital staff's nasal swabs. Two strains were vancomycin-resistant. The serial dilution tube test methodwas used to determine minimum inhibitory concentration (MIC) .The susceptibility of each strain of staph bacteria to natural honey without wax was determined and compared with that of a glucose solution with the same density.

Results: In all strains, except for the two strains resistant to vancomycin, MIC level was < 8.3% (v/v). The MIC of glucose as dense as honey was four times higher. The two vancomycin-resistant strains were completely resistant to natural honey.

Conclusions: This study has therefore demonstrated that inhibiting bacterial growth is not merely done by purely natural honey not because of osmolality, but vancomycin-resistant bacteria are not sensitive to natural honey.

Keywords: sensitivity, Staphylococcus aurous, natural honey, minimum inhibitory concentration

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