Published date: Sep 26 2019

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 14 (2019), Issue No. 3

Pages: 103–115

DOI: 10.18502/sjms.v14i3.5210

Cyrille BISSEYELaboratory of Molecular and Cellular Biology (LABMC) University of Science and Technology of Masuku (USTM)

Jophrette Mireille Ntsame Ndong2National Blood Transfusion Center (NBTC), P.O. Box 13895, Libreville, Gabon

Landry Erik Mombo1Laboratory of Molecular and Cellular Biology (LABMC), University of Science and Technology of Masuku (USTM), P.O. Box 943, Franceville, Gabon

Hornéla Christine Minkoue Mambéri1Laboratory of Molecular and Cellular Biology (LABMC), University of Science and Technology of Masuku (USTM), P.O. Box 943, Franceville, Gabon

Guy Mouelet Migolet2National Blood Transfusion Center (NBTC), P.O. Box 13895, Libreville, Gabon

Gemael Cedrick Taty-Taty1Laboratory of Molecular and Cellular Biology (LABMC), University of Science and Technology of Masuku (USTM), P.O. Box 943, Franceville, Gabon

Bolni Marius Nagalo1Laboratory of Molecular and Cellular Biology (LABMC), University of Science and Technology of Masuku (USTM), P.O. Box 943, Franceville, Gabon

Background: The objective of this study was to determine complete blood count (CBC) abnormalities in Libreville blood donors to advocate for hemoglobin pre-donation implementation and to take into account CBC results in blood donation qualification.

Methods: This retrospective study was conducted with 4573 blood donors in March 2016 and from January to April 2017. CBC was performed using SysmexXP-300^TM hematology analyzer (SYSMEX Corporation, Kobe, Japan).

Results: Blood donors were predominantly males (83.7%) with an age ranging from 18 to 59 years. The abnormalities of leukocyte, platelet and erythrocyte counts were determined in blood donors. Leukopenia and thrombocytopenia were significantly more common in men than women (29.02% vs 24.4%, p = 0.011 and 16.2% vs 7.5%, p <0.001). Only 1.0% of women and 0.84% of men have leukocytosis, and 0.7% of women and 0.2% of men have thrombocytosis. Anemia was significantly more common in women compared to men (69.4% vs. 45.0%, P <0.001). Normocytic normochromic and normocytic hypochromic anemia were most common among Libreville blood donors with 39.4% and 23.6%; followed by microcytic normochromic (18.7%) and microcytic hypochromic (13.2%) anemia. Normocytic normochromic and normocytic hypochromic anemia were significantly more common in men than in women, whereas microcytic normochromic anemia was more prevalent among women compared to men (34.6% vs. 13.9%, p <0.001).

Conclusions: The results of this study clearly show the need to perform a pre-donation hemoglobin test in blood donors and to take into account their hemogram in the blood donation selection process at the Libreville National Blood Transfusion Center.

Keywords: Hemogram, Anemia, Blood Donors, Libreville, Gabon.

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