Published date: Dec 26 2018

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 13 (2018), Issue No. 4

Pages: 240-250

DOI: 10.18502/sjms.v13i4.3596

Najem Aldin Mohammed Osmannajemosman@hotmail.com

Intisar Elhag Elraya

Yassir Mahgoub Mohamed

Muataz Mohamed Eldirdery

Salaheldein Gumaa Elzaki

Abdallah Elssir Ahmed

Ali Mohamed Elhassan Eleragi

Background: Methicillin-resistant Staphylococcus aureus (MRSA) have emerged as an important cause of nosocomial and community-acquired infections ranging from mild to severe life-threatening infections. Therefore, a reliable detection of such strains is required for effective treatment. Objectives: To determine the frequency and the antibiogram of MRSA among different clinical isolates. Study Design: A cross-sectional, descriptive study. Materials and Methods: Standard bacteriological methods, disk diffusion and PCR
were performed to determine the frequency of MRSA among different clinical isolates. Results: The overall results showed 96/210 (45.7%) of isolates were MRSA mostly recovered from wounds and blood stream. High percentage was detected in hospitalassociated (HA) strains (64.2%) rather than community (CA) (37.1%) (P-value < 0.001). From the generated Antibiogram, Co-trimoxazole was the most active (80.2%), while Penicillin was the least one (6.2%). Conclusion: As MRSA strains were mostly isolated from Hospitals, clinicians should be
aware of such burden strains. Local frequency investigation of MRSA is recommended for perfect diagnosis and treatment.

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