Published date:Mar 28 2025

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 20 (2025), Issue No. 1

Pages:91 - 98

DOI: 10.18502/sjms.v20i1.16587

MohamedAhmed M. Ibnoufmaibnouf@gmail.comFaculty of Medicine and Health Sciences, Omdurman Islamic University, Omdurman

Eltahir A. Eltahireltahirahmed75@gmail.comDepartment of Surgery, University of El Fashir, Darfur

Mohammed M.A.M. Ibnoufibn3ouf@gmail.comFaculty of Medicine and Health Sciences, Omdurman Islamic University, Omdurman

Mohamed H. Ahmed0912233062a@gmail.comState Ministry of Health, North Darfur State

Hassan Bashir Alihassanbashir780780@gmail.comFedail Hospital, Khartoum

Mohammed Haroon1mmam787@gmail.comDepartment of Surgery, University of El Fashir, Darfur

Atif Ahmed M. Saadatifasaad71@hotmail.comFaculty of Medicine and Health Sciences, Omdurman Islamic University, Omdurman

Suliman S. Fedailssfedail@yahoo.comDepartment of Medicine and Gastroenterology, Fedail Hospital, Khartoum

Background: Spontaneous pathological rupture of the malarial spleen (SPRMS) is a rare but serious complication that has no known predictor in the medical literature. This study aims to report a systematic review of the search for a predictor for SPRMS and the recent changes in the management trends and outcomes of this problem.

Methods: A systematic review of 122 cases from January of 2000 through March of 2024 was conducted and linear regression was computed to search for predicting factors for SPRMS.

Results: Plasmodium vivax (P. vivax) was the most common cause of SPRMS among local citizens, while Plasmodium falciparum (P. Falciparum) was predominant among infected travelers. Fifty patients underwent splenectomy. Despite being a confounding factor in logistic regression, blood pressure could be the sole predictor of SPRMS.

Conclusion: Recent management trends have shown a tendency toward conservative treatment to preserve splenic immunological functions. To our knowledge, this is the first report on a predicting factor for SPRMS. This is important for early diagnosis and health management, as securing patient safety is a cornerstone of clinical governance in emergency settings.

Keywords: spleen, rupture, malaria

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