Published date: Dec 29 2023

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 18 (2023), Issue No. 4

Pages: 444–452

DOI: 10.18502/sjms.v18i4.14727

Ola Abdoalnasir Abdoalrasol AbdallahDepartment of Chemical Pathology, Faculty of Medical Laboratory Science, University of Medical Science & Technology UMST, Khartoum, Sudan

Hafsa Ahmed Elrheima Ahmedhafsa.ahmed23@yahoo.comDepartment of Chemical Pathology, Faculty of Medical Laboratory Science, University of Medical Science & Technology UMST, Khartoum, Sudan

Background: Type II diabetes is a chronic hyperglycemic disorder. Vitamin D appears to be associated with chronic disease prevention and modulation of immunity. This study was designed to associate vitamin D levels with glycemic control among type 2 diabetes mellitus in Khartoum state.

Methods: This was a prospective case-control study conducted between June and November 2021 in Khartoum, Sudan. In total, 80 individuals were included in the study, of which 40 had type 2 diabetes mellitus, while the other 40 were normal, apparently healthy individuals. Vitamin D was measured by ELISA.

Results: SPSS was used for statistical analysis. Results showed that 20% of the case group (patients with diabetes mellitus) had suboptimal vitamin D levels, whereas 80% had vitamin D deficiency. Vitamin D levels were significantly decreased among the case group when compared to the control group (P-value = 0.00). The glycated hemoglobin was negatively correlated with vitamin D level (P-value = 0.017, R = –0.376).

Conclusion: In this study, a significant decrease in vitamin D was seen among people with type 2 DM. There was a weak negative correlation between hemoglobin A1C and vitamin D levels, and no significant difference in Vitamin D levels among gender and different types of treatment.

Keywords: diabetes mellitus, vitamin D, glycemic control

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