Published date: Jun 28 2024

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 19 (2024), Issue No. 2

Pages: 160–172

DOI: 10.18502/sjms.v19i2.13225

Meisam Dastanimeisam.dastani@gmail.comInfectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran

Jalal Mardanehjalalmardaneh@yahoo.comInfectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran

Reza Ahmadidrahmadi@gmu.ac.irSchool of Medicine, Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran

Background: Since human papillomavirus (HPV) infection is known as one of the main causes of cervical cancer, medical researchers pay significant attention to this issue2. The current study applies the bibliometric method to identify the trends and advancements of research on HPV worldwide.

Methods: This descriptive study was conducted using a bibliometric approach. All HPV-related scientific publications in the Web of Science database until 2022, August 30 were included in the statistical population. The Bibliometrix package of the R programming language was used to analyze the data.

Results: In the field of HPV, a total of 45,657 scientific publications were retrieved, the majority of which were articles. The countries with the highest publications were the USA (45,954 document), China (9977), and UK (6652). The words “Infection,” “Cancer,” and “Women” are the most important keywords of scientific publications on HPV. “Cancer,” “infection,” and “women” are the more developed and essential in HPV subject area. “Protein,” “gene-expression,” and “human-keratinocytes” are in this quadrant. “DNA,” “squamous-cell carcinoma,” and “head” keywords are basic themes in the HPV subject area. “Human-papillomavirus vaccination,” “knowledge,” and “attitude” are in this quadrant.

Conclusion: The study suggests the need to enhance the focus on global and public health aspects within HPV research to encourage greater participation from various countries in international research endeavors.

Keywords: human papillomavirus (HPV), bibliometric, scientific production

[1] Walboomers, J. M., Jacobs, M. V., Manos, M. M., Bosch, F. X., Kummer, J. A., Shah, K. V., Snijders, P. J., Peto, J., Meijer, C. J., & Muñoz, N. (1999). Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. The Journal of Pathology, 189(1), 12–19. https://doi.org/10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F

[2] Chesson, H. W., Dunne, E. F., Hariri, S., & Markowitz, L. E. (2014). The estimated lifetime probability of acquiring human papillomavirus in the United States. Sexually Transmitted Diseases, 41(11), 660–664. https://doi.org/10.1097/OLQ.0000000000000193

[3] Mobini Kesheh, M., & Keyvani, H. (2019). The prevalence of HPV genotypes in Iranian population: An update. Iranian Journal of Pathology, 14(3), 197–205. https://doi.org/10.30699/IJP.2019.90356.1861

[4] Choi, S., Ismail, A., Pappas-Gogos, G., & Boussios, S. (2023). HPV and cervical cancer: A review of epidemiology and screening uptake in the UK. Pathogens (Basel, Switzerland), 12(2), 298. https://doi.org/10.3390/pathogens12020298

[5] Lin, H. W., Yu, T. C., & Ho, Y. S. (2011). A systemic review of human papillomavirus studies: Global publication comparison and research trend analyses from 1993 to 2008. European Journal of Gynaecological Oncology, 32(2), 133–140.

[6] Bruel, S., Dutzer, D., Pierre, M., Botelho-Nevers, E., Pozzetto, B., Gagneux-Brunon, A., Chauvin, F., & Frappé, P. (2021). Vaccination for Human Papillomavirus: A historic and bibliometric study. Human Vaccines & Immunotherapeutics, 17(4), 934–942. https://doi.org/10.1080/21645515.2020.1805991

[7] Vanni, T., Mesa-Frias, M., Sanchez-Garcia, R., Roesler, R., Schwartsmann, G., Goldani, M. Z., & Foss, A. M. (2014). International scientific collaboration in HIV and HPV: A network analysis. PLoS One, 9(3), e93376. https://doi.org/10.1371/journal.pone.0093376

[8] Huang, L., Zhang, Y., Guo, Y., Zhu, D., & Porter, A. L. (2014). Four dimensional Science and Technology planning: A new approach based on bibliometrics and technology roadmapping. Technological Forecasting and Social Change, 81, 39–48. https://doi.org/10.1016/j.techfore.2012.09.010

[9] Chen, T., & Gong, X. (2022). Global research trend analysis of Osmanthus fragrans based on Bibliometrix. Mobile Information Systems, 2022, 4091962. https://doi.org/10.1155/2022/4091962

[10] Yang, L., Sun, T., & Liu, Y. (2017). A bibliometric investigation of flipped classroom research during 2000-2015. International Journal of Emerging Technologies in Learning, 12(06), 178–186. https://doi.org/10.3991/ijet.v12i06.7095

[11] Khasseh, A. A., Soosaraei, M., & Fakhar, M. (2016). Cluster analysis and mapping of Iranian researchers in the field of parasitology: With an emphasis on the co-authorship indicators and H index. Majallah-i Mikrub/Shinasi-i Pizishki-i Iran, 10(2), 63–74.

[12] Janssens, F., Leta, J., Glänzel, W., & De Moor, B. (2006). Towards mapping library and information science. Information Processing & Management, 42(6), 1614–1642. https://doi.org/10.1016/j.ipm.2006.03.025

[13] Dastani, M., Mohammadzadeh, A., Mardaneh, J., & Ahmadi, R. (2022). Topic analysis and mapping of tuberculosis research using text mining and co-word analysis. Tuberculosis Research and Treatment, 2022, 8039046. https://doi.org/10.1155/2022/8039046

[14] Zhong, D., Li, Y., Huang, Y., Hong, X., Li, J., & Jin, R. (2022). Molecular mechanisms of exercise on cancer: A bibliometrics study and visualization analysis via CiteSpace. Frontiers in Molecular Biosciences, 8, 797902. https://doi.org/10.3389/fmolb.2021.797902

[15] Wang, J., & Maniruzzaman, M. (2022). A global bibliometric and visualized analysis of bacteria-mediated cancer therapy. Drug Discovery Today, 27, 103297. https://doi.org/10.1016/j.drudis.2022.05.023

[16] Hao, K. J., Jia, X., Dai, W. T., Huo, Z. M., Zhang, H. Q., Liu, J. W., & Wang, X. B. (2022). Mapping intellectual structures and research hotspots of triple negative breast cancer: A bibliometric analysis. Frontiers in Oncology, 11, 689553. https://doi.org/10.3389/fonc.2021.689553

[17] Zhang, Y., Yu, C., Zhao, F., Xu, H., Zhu, C., & Li, Y. (2022). Landscape of artificial intelligence in breast cancer (2000–2021): A bibliometric analysis. Frontiers in Bioscience (Landmark Edition), 27(8), 224. https://doi.org/10.31083/j.fbl2708224

[18] Shaw, P., Lokhotiya, K., Kumarasamy, C., Sunil, K., Suresh, D., Shetty, S., Muthukaliannan, G. K., Baxi, S., Mani, R. R., Sivanandy, P., Chandramoorthy, H. C., Gupta, M. M., Samiappan, S., & Jayaraj, R. (2022). Mapping Research on miRNAs in cancer: A global data analysis and bibliometric profiling analysis. Pathophysiology, 29(1), 66–80. https://doi.org/10.3390/pathophysiology29010007

[19] Danesh, F., & Ghavidel, S. (2019). GhaviDel S. Visualizing the clusters and dynamics of HPV research area. Majallah-i Mikrub/Shinasi-i Pizishki-i Iran, 13(4), 266–278. https://doi.org/10.30699/ijmm.13.4.266

[20] Danesh, F., & Ghavidel, S. (2020). Visualizing human papillomavirus conceptual network evolution: A global view. Health Information Management, 16(6), 301–307.

[21] Özdemir, Ş., & Şahin, K. (2023). Bibliometric analysis of joint publications on human papilloma virus vaccine and cervical cancer. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 14(1), 61–67. https://doi.org/10.31067/acusaglik.1189152

[22] Aria, M., & Cuccurullo, C. (2017). Bibliometrix: An R-tool for comprehensive science mapping analysis. Journal of Informetrics, 11(4), 959–975. https://doi.org/10.1016/j.joi.2017.08.007

[23] Mühl, D. D., & de Oliveira, L. (2022). A bibliometric and thematic approach to agriculture 4.0. Heliyon, 8(5), e09369. https://doi.org/10.1016/j.heliyon.2022.e09369

[24] Della Corte, V., Del Gaudio, G., Sepe, F., & Sciarelli, F. (2019). Sustainable tourism in the open innovation realm: A bibliometric analysis. Sustainability (Basel), 11(21), 6114. https://doi.org/10.3390/su11216114

[25] Druss, B. G., & Marcus, S. C. (2005). Growth and decentralization of the medical literature: Implications for evidence-based medicine. Journal of the Medical Library Association: JMLA, 93(4), 499–501.

[26] Fontelo, P., & Liu, F. (2018). A review of recent publication trends from top publishing countries. Systematic Reviews, 7(1), 147. https://doi.org/10.1186/s13643-018-0819-1

[27] Aria, M., Misuraca, M., & Spano, M. (2020). Mapping the evolution of social research and data science on 30 years of Social Indicators Research. Social Indicators Research, 149(3), 803–831. https://doi.org/10.1007/s11205-020-02281-3

[28] Kofler, B., Laimer, J., Bruckmoser, E., Steinbichler, T. B., Runge, A., Schartinger, V. H., von Laer, D., & Borena, W. (2020). The role of HPV and non-HPV sexually transmitted infections in patients with oropharyngeal carcinoma: A case control study. Cancers (Basel), 12(5), 1192. https://doi.org/10.3390/cancers12051192

[29] Adegboyega, A., Obielodan, O., Wiggins, A. T., Dignan, M., & Williams, L. B. (2023). Beliefs and knowledge related to human papillomavirus (HPV) vaccine among African Americans and African immigrants young adults. Cancer Causes & Control, 34(5), 479–489. https://doi.org/10.1007/s10552-023-01678-y

[30] Roden, R. B. S., & Stern, P. L. (2018). Opportunities and challenges for human papillomavirus vaccination in cancer. Nature Reviews. Cancer, 18(4), 240–254. https://doi.org/10.1038/nrc.2018.13

[31] Camara, H., Zhang, Y., Lafferty, L., Vallely, A. J., Guy, R., & Kelly-Hanku, A. (2021). Self-collection for HPV-based cervical screening: A qualitative evidence meta-synthesis. BMC Public Health, 21(1), 1503. https://doi.org/10.1186/s12889-021-11554-6

[32] Kombe Kombe, A. J., Li, B., Zahid, A., Mengist, H. M., Bounda, G.-A., Zhou, Y., & Jin, T. (2021). Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation. Frontiers in Public Health, 8, 552028. https://doi.org/10.3389/fpubh.2020.552028

[33] Dadar, M., Chakraborty, S., Dhama, K., Prasad, M., Khandia, R., Hassan, S., Munjal, A., Tiwari, R., Karthik, K., Kumar, D., Iqbal, H. M. N., & Chaicumpa, W. (2018). Advances in designing and developing vaccines, drugs and therapeutic approaches to counter human papilloma virus. Frontiers in Immunology, 9, 2478. https://doi.org/10.3389/fimmu.2018.02478

[34] Mo, Y., Ma, J., Zhang, H., Shen, J., Chen, J., Hong, J., Xu, Y., & Qian, C. (2022). Prophylactic and therapeutic HPV vaccines: Current scenario and perspectives. Frontiers in Cellular and Infection Microbiology, 12, 909223. https://doi.org/10.3389/fcimb.2022.909223

[35] Nasir, A., Shaukat, K., Hameed, I. A., Luo, S., Alam, T. M., & Iqbal, F. (2020). A bibliometric analysis of corona pandemic in social sciences: A review of influential aspects and conceptual structure. IEEE Access: Practical Innovations, Open Solutions, 8, 133377–133402. https://doi.org/10.1109/ACCESS.2020.3008733

[36] Kojic, E. M., & Cu-Uvin, S. (2007). Update: Human papillomavirus infection remains highly prevalent and persistent among HIV-infected individuals. Current Opinion in Oncology, 19(5), 464–469. https://doi.org/10.1097/CCO.0b013e3282c8c84c