Published date: Dec 31 2022

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 17 (2022), Issue No. 4

Pages: 485–497

DOI: 10.18502/sjms.v17i4.12549

Omer Abdalla Elamin Abdelgadir - Omer.Abdelgadir91@gmail.com - https://orcid.org/0000-0003-2662-9627

Amal Mahmoud Saeed

Abubaker Shadoul Mohamed Farah - https://orcid.org/0000-0003-0201-3916

Mohanad Elsebty Mohammed Alhassan Ahmed - https://orcid.org/0000-0002-7994-4826

Mogahid Ahmed Osman Farah - https://orcid.org/0000-0002-2659-878X

Abdelhadi Ahmed Abdelhadi Elsayed - https://orcid.org/0000-0002-5674-2201

Awab Abdalhafiz Altahir Ahmedelbasheir - https://orcid.org/0000-0001-8884-4790

Mahmoud Saeed Saad Mahgoub - https://orcid.org/0000-0003-1695-2121

Ahmed Khalafalla Mohamed Ahmed - https://orcid.org/0000-0003-2886-3046

Background: Hemoglobin A1C (HbA1c) levels are known to be linked to a higher risk of stroke. However, no research data is available on the impact of HbA1C on the severity of acute ischemic stroke in Sudan.
Methods: This study is a descriptive, cross-sectional hospital-based study of 40 cases of acute ischemic stroke. Ischemic stroke was confirmed using computed tomography (CT) scan at admission; all subjects’ blood HbA1C levels were also measured. Participants were divided into two subgroups based on HbA1C at admission, good glycemic control (GGC) (<7 HbA1C) and poor glycemic control (PGC) (>7 HbA1C), and neurological impairment was assessed using the National Institutes of Health Stroke Scale (NIHSS).
Results: The age distribution of the participants was 45-85 years, with an average age of 63.5±9.2 years with the highest frequency (67.5%) in the age group of 55-75 years. PGC had a statistically significant high HbA1C value of 8.9±1.3 (P=0.000), when compared to GGC subgroups 5.1±0. The association between stroke severity and HbA1C levels on admission in this study was statistically significant (P value=0.005), on admission (78.6%) PGC had moderate to severe stroke (> 18.8 NIHSS) versus (33.3%) that of the GGC (>10.4NIHSS). The frequency of elevated HbA1C levels in patients with acute ischemic stroke was 70% in this study.
Conclusion: PGC was shown to be linked to the occurrence of stroke and to its severity.

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