Published date: Mar 31 2022

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 17 (2022), Issue No. 1

Pages: 70-78

DOI: 10.18502/sjms.v17i1.10686

Stalinjit SinghPhD Scholar, Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, Punjab, India

Sudershan KapoorProfessor & Head, Department of Surgery, Government Medical College & Hospital, Amritsar, Punjab, India

Mukesh ChanderAssistant Professor, Department of Biotechnology, Khalsa College, Amritsar, Punjab, India

Prabhjot Gillpjkgill@rediffmail.comDepartment of Biomedical Research, Shri Guru Ram Das University of Health Sciences, Amritsar (Vallah)

Background: Breast carcinoma in females is an ever-growing malaise with significant mortality and morbidity. In resource-poor settings, the need for a cost-effective and reliable diagnostic tool is of utmost importance.

Methods: In the present study, 54 histopathologically proven breast cancer patients were investigated for their pre- and postoperative serum ALP and ACP levels.

Results: A total of 34 cases (belonging to the age interval of 40–60 years) exhibited a significant drop in serum ALP level after surgery (P = 0.002). Although the serum ACP also showed a postoperative decline, it was not as significant as that of serum ALP.

Conclusion: The role of serum ALP and ACP in the diagnosis, prognosis, and monitoring/surveillance of breast carcinoma cannot be underestimated particularly in third-world countries lacking in medical infrastructure or resource-poor settings.

Keywords: alkaline phosphatase, acid phosphatase, breast cancer, malignancy

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