Published date: Mar 08 2023

Journal Title: KnE Medicine

Issue title: 2nd International Conference on Medical Health Science (2nd ICMEDH)

Pages: 540–548

DOI: 10.18502/kme.v3i2.13089

Siti Aisyahfirasti@umm.ac.idFaculty of Health Sciences, Pharmacy Department, Muhammadiyah Malang University

Didik HasmonoFaculty of Pharmacy, Airlangga University

Binti MuzayyanahDr. Iskak Tulungagung Regional Public Hospital

Firasti Agung NSFaculty of Health Sciences, Pharmacy Department, Muhammadiyah Malang University

Hemorrhagic stroke is a condition where one of the arteries in the brain bursts, causing bleeding in that organ. Mannitol is an osmotic diuretic drug often used to correct high intracranial pressure due to bleeding. This research aimed to determine the pattern of mannitol in hemorrhagic stroke at the Inpatient Installation of Dr. Iskak Tulungagung Regional Public Hospital. This was a retrospective observational study with the presentation of data descriptively in patients with hemorrhagic stroke who received mannitol therapy at Inpatient Installation Dr. Iskak Tulungagung Regional Public Hospital. Mannitol was only used alone with the highest dose (2x0.3g/kgBW) for 65 patients (81%). Mannitol was used in single usage with the highest dose (2x0,3g/kg BW) in 65 patients (81%). Mannitol with the most widely dose switching pattern usage is from (6x0,3g/kg BW) iv to (5x0,3g/kg BW) iv to (4x0.3g/kg BW) iv to (3x0.3g/kg BW) iv to (2x0.3g/kg BW) iv to (1x0.3g/kg BW) iv to 11 patients (14%). Mannitol was given by tapering off or decreasing the dose slowly and the duration of use of Mannitol with the highest percentage at 4-7 days in as many as 68 patients (85%).

Keywords: mannitol, hemorrhagic stroke, diuretic osmotic

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