Published date: Mar 08 2023

Journal Title: KnE Medicine

Issue title: 2nd International Conference on Medical Health Science (2nd ICMEDH)

Pages: 136–145

DOI: 10.18502/kme.v3i2.13046

Anis Ika Nur Rohmahanisikanur@umm.ac.idFaculty of Health Science, University of Muhammadiyah Malang, Indonesia

Syanindita Maharani FadjriFaculty of Health Science, University of Muhammadiyah Malang, Indonesia

Adherence in stroke patients for routine re-control is at 50% of total stroke patients. Non-adherence can increase the incidence of recurrent strokes. In stroke recurrence, disability and mortality will increase. This study aimed to determine the factors influencing treatment adherence in stroke patients based on literature studies. This study used a literature study with a sample of 14 journals: Pubmed (n=7), Proquest (n=4), SAGE Journal (n=1), and Science Direct (n=2). The literature study began with identifying data search problems, screening, and quality assessment using JBI cross-sectional studies, cohort studies, qualitative studies, dan Randomized Control trials and analyzed using thematic analysis techniques. As many as 35% of the factors that influence adherence to treatment in stroke patients are beliefs about treatment factors, and social factors and knowledge influence 15% of factors. Economic factors have an estimated percentage of 11% for physical characteristics, and marital status has a rate of 8%; also, age and gender factors have the same presentation, namely 4%. The factor that most influences medication adherence in stroke patients is the belief in the treatment.

Keywords: factors, influence, treatment adherence, stroke patients

[1] Johnson W, Onuma O, Owolabi M, Sachdev S. Stroke: a global response is needed. Bull World Health Organ. 2016 Sep;94(9):634–634A.

[2] Riskesdas. Hasil Utama Riset Kesehatan Dasar. Kementrian Kesehat Republik Indones [Internet]. 2018;1–100. Available from: http://www.depkes.go.id/resources/download/info-terkini/hasil-riskesdas-2018.pdf

[3] Zelko E, Klemenc-Ketis Z, Tusek-Bunc K. KlemencKetis Z, TusekBunc K. Medication Adherence in Elderly with Polypharmacy Living at Home: a Systematic Review of Existing Studies. Mater Sociomed. 2016 Apr;28(2):129–32.

[4] Jamison J, Sutton S, Mant J, De Simoni A. Barriers and facilitators to adherence to secondary stroke prevention medications after stroke: analysis of survivors and caregivers views from an online stroke forum. BMJ Open. 2017 Jul;7(7):16814.

[5] Cholisoh Z, Karuniawati H, Azizah T. Zaenab, Hekmah LN. Faktor-Faktor yang Mempengaruhi Ketidakpatuhan Dalam Melakukan Terapi Pencegahan Sekunder pada Pasien Stroke Iskemik. Jmpf [Internet]. 2018;8(2):90–9. Available from: https://www.scribd.com/document/486391224/4

[6] Al AlShaikh S, Quinn T, Dunn W, Walters M, Dawson J. Predictive factors of nonadherence to secondary preventative medication after stroke or transient ischaemic attack: A systematic review and meta-analyses. Eur Stroke J. 2016 Jun;1(2):65–75.

[7] Ramandha A, Kusmindari CD, Hardini S. Pelaksanaan Total Productive Maintenance Terhadap Kinerja Bucket Wheel Excavator Melalui Cause Effect Diagram (Studi Kasus pada PT Bukit Asam, Tbk). Bina Darma Conf Eng Sci; 2020. pp. 340–54.

[8] Murphy SJ, Coughlan CA, Tobin O, Kinsella J, Lonergan R, Gutkin M, et al. Continuation and adherence rates on initially-prescribed intensive secondary prevention therapy after Rapid Access Stroke Prevention (RASP) service assessment [Internet]. J Neurol Sci. 2016 Feb;361:13–8.

[9] Jamison J, Graffy J, Mullis R, Mant J, Sutton S. Barriers to medication adherence for the secondary prevention of stroke : a qualitative interview study in primary care. The British Journal of General Practice. 2016;(August):568–76. https://doi.org/10.3399/bjgp16X685609.

[10] Characteristic RB, Laily SR, Timur J. Relationship Between Characteristic and Hypertension With Incidence of Ischemic Stroke. 2017 Apr;2016:48–59.

[11] Cheiloudaki E, Alexopoulos EC. Adherence to Treatment in Stroke Patients. Int J Environ Res Public health. 2019; https://doi.org/10.3390/ijerph16020196.

[12] Azizi N, Karimy M, Salahshour VN. Original Article Determinants of adherence to tuberculosis treatment in Iranian patients : Application of health belief model. J Infect Dev Ctries. 2018 Sep 30;12(9):706-711. doi: 10.3855/jidc.9653.

[13] Yue S. The Association Among Medication Beliefs, Perception of Illness and Medication Adherence in Ischemic Stroke Patients : A Cross-Sectional Study in China. Patient Prefer Adherence. 2020;235–47.

[14] Appalasamy JR, Joseph JP. Exploring stroke survivors self-efficacy in understanding and taking medication and determining associated factors : a cross-sectional study in a neurology clinic in Malaysia. Patient Prefer Adherence. . 2019 Aug 28;13:1463-1475. doi: 10.2147/PPA.S215271. eCollection 2019.

[15] Juniastira S. Hidup Pada Pasien Stroke. 2018

[16] Wahyuni S, Dewi C. Faktor-Faktor Yang Berhubungan Dengan Efikasi Diri Pasien Pasca Stroke : Studi Cross Sectional Di Rsud Gambiran Kediri Factors Associated With Self-Efficacy Of Post-Stroke Patients : A Cross-Sectional Study In Gambiran Kediri. 2018;85–92.

[17] Rohde D, Merriman NA, Doyle F, Bennett K, Williams D, Hickey A. Does cognitive impairment impact adherence? A systematic review and meta-analysis of the association between cognitive impairment and medication non-adherence in stroke. PLoS One. 2017 Dec;12(12):189339.

[18] Jiang Y, Yang X, Li Z, Pan Y, Wang Y, Wang Y, et al. Persistence of secondary prevention medication and related factors for acute ischemic stroke and transient ischemic attack in China [Internet]. Neurol Res. 2017 Jun;39(6):492–7.

[19] Eriksson M, Glader E, Sjo M. Inequalities in medication adherence to statin treatment after stroke : A nationwide observational study. Eur Stroke J. 2016 Jun;1(2):101-107. doi: 10.1177/2396987316646026. Epub 2016 Apr 21.

[20] Jiang F, Deng L, Zhang L, Cai Y, Cheung CW, Xia Z. Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19). J Gen Intern Med 2020 May;35(5):1545-1549. doi: 10.1007/s11606-020-05762-w. Epub 2020 Mar 4.