Published date:Dec 27 2022

Journal Title: KnE Life Sciences

Issue title: Science and Technology Research Symposium (SIRES)

Pages:219–224

DOI: 10.18502/kls.v7i5.12529

S. Suwendarsuwendar-suwendar48@gmail.comDepartment of Pharmacist Professional Education, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

L. WahidahDepartment of Pharmacy, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

Y. KrisnamurtiDepartment of Statistics, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

M. L. RidwanDepartment of Statistics, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

W. LestariDepartment of Statistics, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

D. MardliyaniDepartment of Statistics, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

N. FitrianiDepartment of Statistics, Faculty of Mathematics and Natural Science, Universitas Islam Bandung, Bandung, Indonesia

Fungal infection has a high prevalence rate in the feminine area. The use of natural anti-fungal, natural feminine cleansers can be a solution to this problem. Apple rose leaves are thought to be an alternative active ingredient to be developed into a natural feminine area cleanser. In this study, in vitro antifungal activity of guava leaves was observed on Candidia albicans and their development into a feminine area cleanser. The results based on the ethanol extract, n-hexane fraction, ethyl acetate fraction and water fraction showed that there were high anti-fungal properties. The highest anti-fungal effect was shown by the n-hexane fraction. A feminine area cleanser was developed with the n-hexane fraction of apple rose leaves as the active ingredient. Pharmaceutic evaluation showed that the formulation obtained was milky white, odorless, homogeneous, produced foam with a height of 0.5 cm and had a pH of 4.5. Based on the results of the study, it can be concluded that apple rose leaves have the potential to be developed into a feminine area cleanser.

Keywords: apple rose leaves, leukorrhea, natural anti-leukorrhea, feminine area cleansing preparation

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