KnE Engineering

ISSN: 2518-6841

The latest conference proceedings on all fields of engineering.

Register for Content Alerts
Navigation

Customised design of a patient specific 3D printed whole mandible implant

Published date: Feb 09 2017

Journal Title: KnE Engineering

Issue title: The International Conference on Design and Technology

Pages: 104-111

DOI: 10.18502/keg.v2i2.602

Authors:
Abstract:

In this study we investigate the design methodology for the creation of a patient specific, whole mandible implant based on a patient’s medical imaging data. We tailor the implant as a treatment option for a patient who will undergo a mandibulectomy due to cancer infiltration of the jaw. We create a 3D representative model of the patient’s skeletal structure from CT scan data, and us this to generate the implant from the patient’s corrupt mandible. In this particular case study the cancer is restricted to the right region of the mandible, and so the left side is used in a symmetry matching approach to create the final model for manufacturing. The final design was 3D printed in medical grade titanium and finished using a mechanical polishing technique, the yield a near mirror finish. We found the final implant to be highly robust, and an excellent fit to a representative model of the patient’s skeletal anatomy. We believe this approach to hold considerable potential for implementation as a treatment option for mandibular complications. 

References:

[1] R. Singh, T. Kamal, N. Roulohamin, G. Maoharan, B. Ahmed, and P. Theobald, Ankle Fractures: A Literature Review of Current Treatment Methods, Open Journal of Orthopaedics, 4, 292–303, (2014), 10.4236/ojo.2014.411046.


[2] S. V. Casting, Principles of casting and splinting, (2009).


[3] R. Y. Hsu, and J.A.S.O.N. Bariteau, Management of ankle fractures, RI Med J, 96, no. 5, 23–7, (2013).


[4] A. M. Scott, Diagnosis and treatment of ankle fractures, Radiologic technology, 81, no. 5, 457–475, (2010).


[5] C. R. Labella, Common acute sports-related lower extremity injuries in children and adolescents, Clinical Pediatric Emergency Medicine, 8, no. 1, 31–42, (2007), 10.1016/j.cpem.2007.02.010.


[6] N. Hopkinson, R. Hague, and P. Dickens, Rapid Manufacturing: An Industrial Revolution for the Digital Age, John Wiley & Sons, New York, NY, USA, (2006).


[7] I. Gibson, D. W. Rosen, and B. Stucker, Additive Manufacturing Technologies: Rapid Prototyping to Direct Digital Manufacturing, Springer, Berlin, Germany, (2010).


[8] B. Sanghera, S. Naique, Y. Papaharilaou, and A. Amis, Preliminary study of rapid prototype medical models, Rapid Prototyping Journal, 7, no. 5, 275–284, (2001), 10.1108/13552540110410486.


[9] F. Rengier, A. Mehndiratta, H. von Tengg-Kobligk, et al., 3D printing based on imaging data: review of medical applications, International Journal of Computer Assisted Radiology and Surgery, 5, no. 4, 335–341, (2010), 10.1007/s11548-010-0476-x.

Download
HTML
Cite
Share
Crossref Cited-by logo

37

Sheng-Ni Huang, Ming-You Shie, Yen-Wen Shen, Jui-Ting Hsu, Heng-Li Huang, Lih-Jyh Fuh (2019)

Biomechanical Assessment of Design Parameters on a Self-Developed 3D-Printed Titanium-Alloy Reconstruction/Prosthetic Implant for Mandibular Segmental Osteotomy Defect, Metals

Volume: 9, Issue: 5, First Page: 597

10.3390/met9050597

Mazher I. Mohammed, Brenton Cadd, Greg Peart, Ian Gibson (2018)

Augmented patient-specific facial prosthesis production using medical imaging modelling and 3D printing technologies for improved patient outcomes, Virtual and Physical Prototyping

Volume: 13, Issue: 3, First Page: 164

10.1080/17452759.2018.1446122

Mazher Iqbal Mohammed, Ian Gibson (2018)

Design of Three-Dimensional, Triply Periodic Unit Cell Scaffold Structures for Additive Manufacturing, Journal of Mechanical Design

Volume: 140, Issue: 7

10.1115/1.4040164

Gabriel Gaal, Vladimir Gaal, Maria Luisa Braunger, Antonio Riul, Varlei Rodrigues (2020)

FDM 3D Printing in Biomedical and Microfluidic Applications,

First Page: 127

10.1007/978-981-15-5424-7_6

Afnan AlRawi, Tasneem Basha, Ahmed O Elmeligy, Noha A Mousa, Ghada Mohammed (2023)

The Role of Three-dimensional Printed Models in Women’s Health, Women's Health

Volume: 19

10.1177/17455057231199040

Jelena R. Milovanovic, Milos S. Stojkovic, Karim N. Husain, Nikola D. Korunovic, Jovan Arandjelovic, Saverio Maietta (2020)

Holistic Approach in Designing the Personalized Bone Scaffold: The Case of Reconstruction of Large Missing Piece of Mandible Caused by Congenital Anatomic Anomaly, Journal of Healthcare Engineering

Volume: 2020, First Page: 1

10.1155/2020/6689961

Mazher Iqbal Mohammed, Daniel Wilson, Eli Gomez-Kervin, Bin Tang, Jinfeng Wang (2019)

Investigation of Closed-Loop Manufacturing with Acrylonitrile Butadiene Styrene over Multiple Generations Using Additive Manufacturing, ACS Sustainable Chemistry & Engineering

Volume: 7, Issue: 16, First Page: 13955

10.1021/acssuschemeng.9b02368

Richard Bibb, Dominic Eggbeer, Abby Paterson, Mazher Iqbal Mohammed (2024)

Surgical applications case study 8—Virtual surgical planning and development of a patient-specific resection guide for treatment of distal radius osteosarcoma,

First Page: 261

10.1016/B978-0-323-95733-5.15002-1

Nihal Engin Vrana, Sharda Gupta, Kunal Mitra, Albert A. Rizvanov, Valeriya V. Solovyeva, Ezgi Antmen, Majid Salehi, Arian Ehterami, Lea Pourchet, Julien Barthes, Christophe A. Marquette, Magnus von Unge, Chi-Yun Wang, Po-Liang Lai, Arindam Bit (2022)

From 3D printing to 3D bioprinting: the material properties of polymeric material and its derived bioink for achieving tissue specific architectures, Cell and Tissue Banking

Volume: 23, Issue: 3, First Page: 417

10.1007/s10561-021-09975-z

Rohan Prabhu, Timothy W. Simpson, Scarlett R. Miller, Nicholas A. Meisel (2021)

Fresh in My Mind! Investigating the effects of the order of presenting opportunistic and restrictive design for additive manufacturing content on students’ creativity, Journal of Engineering Design

Volume: 32, Issue: 4, First Page: 187

10.1080/09544828.2021.1876843

Rohan Prabhu, Scarlett R. Miller, Timothy W. Simpson, Nicholas A. Meisel (2020)

But Will It Build? Assessing Student Engineering Designers’ Use of Design for Additive Manufacturing Considerations in Design Outcomes, Journal of Mechanical Design

Volume: 142, Issue: 9

10.1115/1.4046071

Jaejong Park, Tareq Zobaer, Alok Sutradhar (2021)

A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants, Micromachines

Volume: 12, Issue: 2, First Page: 101

10.3390/mi12020101

Rohan Prabhu, Timothy W. Simpson, Scarlett R. Miller, Nicholas A. Meisel (2022)

Development and validity evidence investigation of a design for additive manufacturing self-efficacy scale, Research in Engineering Design

Volume: 33, Issue: 4, First Page: 437

10.1007/s00163-022-00392-1

Richard Bibb, Dominic Eggbeer, Abby Paterson, Mazher Iqbal Mohammed (2024)

Prosthetic rehabilitation applications case study 11—Augmented patient-specific facial prosthesis production using medical imaging modeling and 3D printing technologies for improved patient outcomes,

First Page: 421

10.1016/B978-0-323-95733-5.00027-2

Chrysoula Chatzigeorgiou, Boris Piotrowski, Fodil Meraghni, Yves Chemisky (2025)

Multiscale mechanical analysis for biomimetic implant design based on Triply Periodic Minimal Surfaces (TPMS) lattices: Application to partial replacement of femoral bone, Results in Engineering

Volume: 25, First Page: 103984

10.1016/j.rineng.2025.103984

Md. Hazrat Ali, Nurbol Sabyrov, Essam Shehab (2022)

Powder bed fusion–laser melting (PBF–LM) process: latest review of materials, process parameter optimization, application, and up-to-date innovative technologies, Progress in Additive Manufacturing

Volume: 7, Issue: 6, First Page: 1395

10.1007/s40964-022-00311-9

Gurminder Singh, Pulak M. Pandey (2020)

Role of Imaging Data in Additive Manufacturing for Biomedical Applications,

First Page: 69

10.1007/978-981-15-5424-7_4

Ruixiu Li, Yu-Huan Ting, Souha Youssef, Yunmei Song, Sanjay Garg (2021)

Three-Dimensional Printing for Cancer Applications: Research Landscape and Technologies, Pharmaceuticals

Volume: 14, Issue: 8, First Page: 787

10.3390/ph14080787

Hasan Kemal Surmen, Faruk Ortes, Yunus Ziya Arslan (2020)

Fundamentals of 3D Printing and Its Applications in Biomedical Engineering,

First Page: 23

10.1007/978-981-15-5424-7_2

Rohan Prabhu, Timothy W. Simpson, Scarlett R. Miller, Stephanie L. Cutler, Nicholas A. Meisel (2023)

Teaching Designing for Additive Manufacturing: Formulating Educational Interventions That Encourage Design Creativity, 3D Printing and Additive Manufacturing

Volume: 10, Issue: 2, First Page: 356

10.1089/3dp.2021.0087

Andreas Engels, Mike Thomas Hauschultz, Hannes Jacobs, Andreas H. Foitzik (2023)

High Volume 3D Printer and Developed of High-Volume Extruders for Gelatin and Liquids, Key Engineering Materials

Volume: 964, First Page: 143

10.4028/p-suFK67

G. Caiti, J. G. G. Dobbe, A. C. Y. Loenen, M. Beerens, S. D. Strackee, G. J. Strijkers, G. J. Streekstra (2019)

Implementation of a semiautomatic method to design patient-specific instruments for corrective osteotomy of the radius, International Journal of Computer Assisted Radiology and Surgery

Volume: 14, Issue: 5, First Page: 829

10.1007/s11548-018-1896-2

Rohan Prabhu, Scarlett R. Miller, Timothy W. Simpson, Nicholas A. Meisel (2020)

Teaching Design Freedom: Understanding the Effects of Variations in Design for Additive Manufacturing Education on Students’ Creativity, Journal of Mechanical Design

Volume: 142, Issue: 9

10.1115/1.4046065

Mohammad J. Mirzaali, Vahid Moosabeiki, Seyed Mohammad Rajaai, Jie Zhou, Amir A. Zadpoor (2022)

Additive Manufacturing of Biomaterials—Design Principles and Their Implementation, Materials

Volume: 15, Issue: 15, First Page: 5457

10.3390/ma15155457

Patrícia Krištofová, Michaela Roudnická, Jiří Kubásek, David Paloušek, Jan Suchý, Dalibor Vojtěch (2019)

Influence of Production Parameters on the Properties of 3D Printed Magnesium Alloy Mg-4Y-3RE-Zr (WE43), Manufacturing Technology

Volume: 19, Issue: 4, First Page: 613

10.21062/ujep/343.2019/a/1213-2489/MT/19/4/6013

Richard Bibb, Dominic Eggbeer, Abby Paterson, Mazher Iqbal Mohammed (2024)

Orthotic applications case study 6—Design optimization of a thermoplastic splint,

First Page: 539

10.1016/B978-0-323-95733-5.00034-X

Andrew Hagen, Megan Chisling, Kevin House, Tal Katz, Laila Abelseth, Ian Fraser, Stephen Bradley, Rebecca Kirsch, Jacob Morris, Joshua W. Giles, Stephanie M. Willerth (2021)

3D Printing for Medical Applications: Current State of the Art and Perspectives during the COVID-19 Crisis, Surgeries

Volume: 2, Issue: 3, First Page: 244

10.3390/surgeries2030025

Rohan Prabhu, Jennifer Bracken, Clinton B. Armstrong, Kathryn Jablokow, Timothy W. Simpson, Nicholas A. Meisel (2020)

Additive creativity: investigating the use of design for additive manufacturing to encourage creativity in the engineering design industry, International Journal of Design Creativity and Innovation

Volume: 8, Issue: 4, First Page: 198

10.1080/21650349.2020.1813633

Răzvan Păcurar, Gania Consuella, Emilia Sabău, Dan Sorin Comşa, Cristina Borzan, Nikola Vitkovic, Sven Maričić, Stanislaw Legutko, Ancuţa Păcurar (2024)

Research on Design and Manufacturing of PEKK-Based Mandibular Implants by Fused Deposition Modeling,

First Page: 108

10.1007/978-3-031-56456-7_9

Dajana Miljanovic, Mehdi Seyedmahmoudian, Alex Stojcevski, Ben Horan (2020)

Design and Fabrication of Implants for Mandibular and Craniofacial Defects Using Different Medical-Additive Manufacturing Technologies: A Review, Annals of Biomedical Engineering

Volume: 48, Issue: 9, First Page: 2285

10.1007/s10439-020-02567-0

Lun Yan, Xingce Wang, Zhongke Wu (2022)

Example-oriented full mandible reconstruction based on principal component analysis, Multimedia Tools and Applications

Volume: 81, Issue: 23, First Page: 34009

10.1007/s11042-022-12454-6

Regalla Rakesh Reddy, Kode Jaya Prakash, Sayina Koteswari, Arvind Ud, Balla Srinivasa Prasad, Y.Shivraj Narayan (2021)

Additive manufacturing of a human mandible and Finite element analysis of dental implant for prosthodontic applications, Materials Today: Proceedings

Volume: 45, First Page: 3028

10.1016/j.matpr.2020.12.055

Kamalpreet Sandhu, Gurminder Singh, Sunpreet Singh, Raman Kumar, Chander Prakash, Seeram Ramakrishna, Grzegorz Królczyk, Catalin I. Pruncu (2020)

Surface Characteristics of Machined Polystyrene with 3D Printed Thermoplastic Tool, Materials

Volume: 13, Issue: 12, First Page: 2729

10.3390/ma13122729

J.P. Ribeiro, Esteban A. Astudillo-Ortiz, Pedro S. Babo, Manuela E. Gomes (2020)

Tissue engineering strategies for the treatment of skeletal maxillofacial defects resulting from neoplasms resections,

First Page: 697

10.1016/B978-0-12-818128-7.00028-9

Senthil Maharaj Kennedy, Amudhan K, Jerold John Britto J, Ezhilmaran V, Jeen Robert RB (2024)

Transformative applications of additive manufacturing in biomedical engineering: bioprinting to surgical innovations, Journal of Medical Engineering & Technology

Volume: 48, Issue: 4, First Page: 151

10.1080/03091902.2024.2399017

Maeve M Kennedy, Antonios G Mikos (2025)

Biomaterials-based approaches to mandibular tissue engineering: where we were, where we are, where we are going, Regenerative Biomaterials

Volume: 12

10.1093/rb/rbaf024