Journal of Ophthalmic and Vision Research

ISSN: 2008-322X

The latest research in clinical ophthalmology and the science of vision.

Does Long-Term Night Shift Work Cause Dry Eye in Hospital Nurses?

Published date: Nov 30 2023

Journal Title: Journal of Ophthalmic and Vision Research

Issue title: Oct–Dec 2023, Volume 18, Issue 4

Pages: 351–358

DOI: 10.18502/jovr.v18i4.14543

Authors:

Aria BouyehNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran

Hassan HashemiNoor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran

Yousef AlizadehEye Research Center, Guilan University of Medical Sciences, Rasht, Iran

Ebrahim Jafarzadehpurjafarzadehpour.e@iums.ac.irRehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran

Ali Mirzajanijafarzadehpour.e@iums.ac.irRehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran

Hadi OstadimoghaddamRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Abbasali YektaRefractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Abolfazl JafarzadehpourNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran

Arghavan ZareiNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran

Mehdi KhabazkhoobDepartment of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract:

Purpose: To determine the long-term effects of night shift work on dry eye in hospital nurses.
Methods: Each participant was evaluated four times, including at the beginning of the day shift (8 am), at the end of the day shift (2 pm), at the beginning of the night shift (8 pm), and at the end of the night shift (8 am), using the tear break-up time (TBUT) test and ocular surface disease index (OSDI) questionnaire.
Results: The results showed significant differences in the TBUT and OSDI between the end of the day shift (2 pm) (10.26, 16.61) and the end of the night shift (8 am) (6.89, 38.59) relative to each other and relative to the beginning of the day and night shifts. As for the correlation between TBUT and OSDI, a significant correlation was found at all measurement times (correlation coefficient: −0.478, −0.707, −0.556, and −0.365, respectively) (p < 0.05).
Conclusion: The results showed that the severity of dry eye increased after the night shift with variation over a 24-hr period. Moreover, a significant correlation was observed between TBUT and OSDI results at the beginning and at the end of the day and night shifts.

References:

1. Arendt J. Melatonin and the pineal gland: Influence on mammalian seasonal and circadian physiology. Rev Reprod 1998;3:13–22.

2. Dibner C, Schibler U, Albrecht U. The mammalian circadian timing system: Organization and coordination of central and peripheral clocks. Annu Rev Physiol 2010;72:517–549.

3. Leproult R, Copinschi G, Buxton O, Van Cauter E. Sleep loss results in an elevation of cortisol levels the next evening. Sleep 1997;20:865–870.

4. Hodges RR, Dartt DA. Regulatory pathways in lacrimal gland epithelium. Int Rev Cytol 2003;231:129–196.

5. Gillan W. Tear biochemistry: A review. African Vis Eye Health 2010;69:100–106.

6. Lee YB, Koh JW, Hyon JY, Wee WR, Kim JJ, Shin YJ. Sleep deprivation reduces tear secretion and impairs the tear film. Invest Ophthalmol Vis Sci 2014;55:3525–3531.

7. Makateb A, Torabifard H. Dry eye signs and symptoms in night-time workers. J Curr Ophthalmol 2017;29:270–273.

8. Begley CG, Chalmers RL, Abetz L, Venkataraman K, Mertzanis P, Caffery BA, et al. The relationship between habitual patient-reported symptoms and clinical signs among patients with dry eye of varying severity. Invest Ophthalmol Vis Sci 2003;44:4753–4761.

9. Foster RG, Kreitzman L. The rhythms of life: What your body clock means to you! Exp Physiol 2014;99:599–606.

10. Grubbs JR, Tolleson-Rinehart S, Huynh K, Davis RM. A review of quality of life measures in dry eye questionnaires. Cornea 2014;33:215–218.

11. Methodologies to diagnose and monitor dry eye disease: Report of the diagnostic methodology subcommittee of the international dry eye workShop (2007). Ocul Surf 2007;5:108–152

12. Phadatare SP, Momin M, Nighojkar P, Askarkar S, Singh KK. A comprehensive review on dry eye disease: Diagnosis, medical management, recent developments, and future challenges. Adv Pharm 2015;2015.

13. Patil SD, Trivedi HR, Parekh N, Jethva J. Evaluation of dry eye in computer users. Int J Community Med Public Health 2016;3:3403–3407.

14. Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the ocular surface disease index. Arch Ophthalmol 2000;118:615–621.

15. Miller KL, Walt JG, Mink DR, Satram-Hoang S, Wilson SE, Perry HD, et al. Minimal clinically important difference for the ocular surface disease index. Arch Ophthalmol 2010;128:94–101.

16. Tian L, Qu JH, Zhang XY, Sun XG. Repeatability and reproducibility of noninvasive keratograph 5M measurements in patients with dry eye disease. J Ophthalmol 2016;2016:8013621.

17. Kawashima M, Uchino M, Yokoi N, Uchino Y, Dogru M, Komuro A, et al. The association of sleep quality with dry eye disease: The Osaka study. Clin Ophthalmol 2016;10:1015–1021.

18. Han KT, Nam JH, Park EC. Do sleep disorders positively correlate with dry eye syndrome? Results of national claim data. Int J Environ Res Public Health 2019;16.

19. Walker PM, Lane KJ, Ousler GW, 3rd, Abelson MB. Diurnal variation of visual function and the signs and symptoms of dry eye. Cornea 2010;29:607–612.

20. Puinhas A, Sampaio P, Castanheira EM, Real Oliveira ME, Lira M. Comparison of IgA, TNF-alpha and surface tension of the tear film in two different times of the day. Cont Lens Anterior Eye 2013;36:140–145.

21. Lira M, Oliveira ME, Franco S. Comparison of the tear film clinical parameters at two different times of the day. Clin Exp Optom 2011;94:557–562.

22. Ozcura F, Aydin S, Helvaci MR. Ocular surface disease index for the diagnosis of dry eye syndrome. Ocul Immunol Inflamm 2007;15:389–393.

23. von Treuer K, Norman TR, Armstrong SM. Overnight human plasma melatonin, cortisol, prolactin, TSH, under conditions of normal sleep, sleep deprivation, and sleep recovery. J Pineal Res 1996;20:7–14.

24. Sullivan DA. Tearful relationships? Sex, hormones, the lacrimal gland, and aqueous-deficient dry eye. Ocul Surf 2004;2:92–123.

25. Whitwell J. Denervation of the lacrimal gland. Br J Ophthalmol 1958;42:518–525.

26. Aicher SA, Hermes SM, Hegarty DM. Denervation of the lacrimal gland leads to corneal hypoalgesia in a novel rat model of aqueous dry eye disease. Invest Ophthalmol Vis Sci 2015;56:6981–6989.

27. Nascimento DC, Andersen ML, Hipolide DC, Nobrega JN, Tufik S. Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain mu-opioid receptors. Behav Brain Res 2007;178:216–220.

28. Patel S, Bevan R, Farrell JC. Diurnal variation in precorneal tear film stability. Am J Optom Physiol Opt 1988;65:151– 154.

29. Guillon M, Shah S. Rationale for 24-hour management of dry eye disease: A review. Contact Lens and Anterior Eye 2019;42:147–154.

30. Bitton E, Keech A, Jones L, Simpson T. Subjective and objective variation of the tear film pre-and post-sleep. Optom Vis Sci 2008;85:740–749.

31. Toda I, Fujishima H, Tsubota K. Ocular fatigue is the major symptom of dry eye. Acta Ophthalmol (Copenh). 1993;71:347–352. 358

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