Journal of Ophthalmic and Vision Research
ISSN: 2008-322X
The latest research in clinical ophthalmology and the science of vision.
Intraocular Pressure Values using Icare® Rebound Tonometer and Correlation with Postconceptional Age in Premature Infants
Published date: Jul 23 2023
Journal Title: Journal of Ophthalmic and Vision Research
Issue title: July–September 2023, Volume 18, Issue 3
Pages: 267–271
Authors:
Abstract:
Purpose: This study aimed to determine a normative range of intraocular pressure (IOP) values measured with Icare rebound tonometer in premature infants and evaluate IOP variation over time and its correlation with the progression of postconceptional age (PCA). By doing so, we also evaluated advantages of this IOP-measuring method in this population when compared to more traditional methods.
Methods: We conducted a single-center prospective study that included premature infants (gestational age ≤32 weeks) who were admitted to the neonatal intensive care unit (NICU) in Hospital Professor Doutor Fernando Fonseca. The study took place between January and December 2021. IOP was measured using Icare tonometer on the occasion of the first retinopathy of prematurity (ROP) screening requested by the NICU and again after a two-week interval if PCA was still ≤37 weeks. IOP measurements were stopped at 37 weeks or if the infant was discharged. The evaluated outcomes were mean IOP values and their correlation with PCA.
Results: Thirty-four eyes of 17 preterm infants with a mean gestational age of 29.4 ± 2.3 weeks and a mean birth weight of 1222.9 ± 361.9 gr were evaluated. The mean IOP registered was 16.1 ± 6.4 mmHg, with a median value of 15.3 mmHg. The top 90 mmHg. The average IOP reduction was 4.8 ± 6.7 mmHg (P = 0.0019) within the two-week interval of PCA.
Conclusion: The mean IOP in premature infants was 16.1 ± 6.4 mmHg and this value significantly
decreased by 4.8 ± 6.7 mmHg every two weeks of PCA.
Keywords: Intraocular Pressure; Postconceptional Age; Premature Infants; Rebound Tonometry
References:
1. Tucker SM, Enzenauer RW, Levin AV, Morin JD, Hellmann J. Corneal diameter, axial length, and intraocular pressure in premature infants. Ophthalmology 1992;99:1296–1300.
2. Kobayashi H, Kiryu J, Kobayashi K, Kondo, T. Ultrasound biomicroscopic measurement of anterior chamber angle in premature infants. Br J Ophthalmol 1997;81:460–464.
3. Ricci B. Intraocular pressure in premature babies in the first month of life. J AAPOS 1999;3:125–127.
4. Ng PC, Tam BS, Lee CH, Wong SP, Lam HS, Kwok AK, et al. A longitudinal study to establish the normative value and to evaluate perinatal factors affecting intraocular pressure in preterm infants. Invest Ophthalmol Vis Sci 2008;49:87– 92.
5. McKibbin M, Cassidy L, Dabbs TR, Verma D, McKibbin M. Intraocular pressure, pulse amplitude and pulsatile ocular blood flow measurement in premature infants screened for retinopathy of prematurity. Eye 1999;13:266–267.
6. Axer-Siegel R, Bourla D, Friling R, Shalev B, Sirota L, Benjamini Y, et al. Intraocular pressure variations after diode laser photocoagulation for threshold retinopathy of prematurity. Ophthalmology 2004;111:1734–1738.
7. Lindenmeyer RL, Farias L, Mendonça T, Fortes Filho JB, Procianoy RS, Silveira RC. Intraocular pressure in very low birth weight preterm infants and its association with postconceptional age. Clinics 2012;67:1241–1245.
8. Epley KD, Tychsen L, Lueder GT. The effect of an eyelid speculum on intraocular pressure measurement in children. Am J Ophthalmol 2002;134:926–927.
9. Lenis TL, Ledesma Vicioso N, Reddy V, Kovacs KD, Van Tassel SH, Orlin A. Case report: Glaucoma in an infant with retinopathy of prematurity. Front Pediatr 2021;9:786327.
10. Haus AH, Jonescu-Cuypers C, Seitz B, Kaesmann-Kellner B. Comparison between intraocular pressure measurements with ICare rebound tonometry and tonopen XL tonometry in premature infants. Invest Ophthalmol Vis Sci 2008;49:712.
