Journal of Ophthalmic and Vision Research

ISSN: 2008-322X

The latest research in clinical ophthalmology and the science of vision.

Effect of Phacoemulsification on Intraocular Pressure in Eyes with Functioning Tube Shunts

Published date: Apr 19 2023

Journal Title: Journal of Ophthalmic and Vision Research

Issue title: April–June 2023, Volume 18, Issue 2

Pages: 150–156

DOI: 10.18502/jovr.v18i2.13180

Authors:

Wesam Shamseldin Shalabywshalaby@willseye.orgWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Sonali PatelSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA

Sophia LamSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA

Allen GanjeiCollege of Medicine, Drexel University, Philadelphia, PA, USA

Aakriti Garg ShuklaWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Natasha KolomeyerWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Daniel LeeWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

L. Jay KatzWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Marlene MosterWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Jonathan MyersWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Reza RazeghinejadWills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA

Abstract:

Purpose: To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in eyes with functioning tube shunts.

Methods: This was a retrospective chart review of primary open-angle glaucoma (POAG) patients with a functioning tube who underwent phacoemulsification and had ≥24 months of follow-up. The primary end point was defined as surgical failure (IOP > 21 mmHg) at month 24, progression to no light perception (NLP) vision, glaucoma reoperation, or implant removal. Surgical failure defined as IOP >18 and >15 mmHg, changes in visual acuity (VA), IOP, and number of medications were assessed.

Results: Twenty-seven eyes of 27 patients with moderate or severe POAG were included. The mean age of the patients was 64.2 ± 10.8 years. The interval between the tube shunt and phacoemulsification was 28.8 ± 25.0 months. At the end of the study, four (14.8%) eyes met the failure criteria; the average time to failure was 9.3 ± 3.8 months. The causes of failure were high IOP in two (50.0%) and glaucoma reoperation in two (50.0%) eyes; however, no eyes progressed to NLP vision. Surgical failure defined as IOP >18 and >15 mmHg showed an increasing failure rate (18.5% and 48.5%, respectively). The mean IOP and medications number remained stable at month 24 compared to baseline (P = 0.131 and P = 0.302, respectively). Initially, VA showed improvement, with the greatest improvement at 6 months (P = 0.001), but at 24 months the improvement was no longer significant (P = 0.430).

Conclusion: Phacoemulsification in patients with functioning tubes did not change the mean IOP in most of the patients (86.2%); the number of medications also did not increase.

Keywords: Cataract Extraction, Glaucoma Drainage Implants, Intraocular Pressure, Phacoemulsification

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