Published date: Jul 02 2020

Journal Title: International Journal of Reproductive BioMedicine

Issue title: International Journal of Reproductive BioMedicine (IJRM): Volume 18, Issue No. 6

Pages: 471–476

DOI: 10.18502/ijrm.v13i6.7288

Firouzeh Ghaffarighafaryf@yahoo.comDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Shokouholsadat MiralaieDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Zahra ChekiniDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Maziar FaridiDepartment of Surgery, Iranmehr Hospital, Tehran, Iran.

Background: Genital tuberculosis is a common cause of infertility due to blocked and permanently damaged fallopian tubes.

Case: In this case report, we describe one extremely rare case of tuberculous salpingitis in a woman who presented with infertility. She received anti-tuberculosis (TB) treatment 10 yr prior. In vitro fertilization (IVF) and intracytoplasmic sperm injection were carried out in our institute. Then, she underwent a laparoscopic salpingectomy due to bilateral hydrosalpinx and a frozen embryo was transferred, which led to pregnancy and a healthy child.

Conclusion: It was concluded that IVF and frozen embryo transfer provides treatment for tubal TB with a receptive endometrium. Laparoscopic salpingectomy prior to embryo transfer plays a critical role in predicting the occurrence of a pregnancy in a patient with hydrosalpingitis attributed to TB.

Key words: In vitro fertilization, Embryo transfer, Female genital tuberculosis, Salpingitis.

[1] Gatongi DK, Gitau G, Kay V, Ngwenya S, Lafong C, Hasan A. Female genital tuberculosis. Obstet Gynaecol 2005; 7: 75–79.

[2] Shahzad S. Investigation of the prevalence of female genital tract tuberculosis and its relation to female infertility: An observational analytical study. Iran J Reprod Med 2012; 10: 581–588.

[3] Sharma JB. Current Diagnosis and Management of Female Genital Tuberculosis. J Obstet Gynecol India 2015; 65: 362–371.

[4] Bapna N, Swarankar M, Kotia N. Genital tuberculosis and its consequences on subsequent fertility. J Obstet Gynaecol India 2005; 55: 534–537.

[5] Organization WH. WHO laboratory manual for the examination and processing of human semen. 5th Ed. World Health Organization Presss, Switzerland; 2010.

[6] Darwish AM, El Saman AM. Is there a role for hysteroscopic tubal occlusion of functionless hydrosalpinges prior to IVF/ICSI in modern practice? Acta Obstet Gynecol Scand 2007; 86: 1484–1489.

[7] Jameson LJ, Fauci A, Kasper D, Hauser S, Longo D, Loscalzo J. Harrison’s principles of internal medicine. 20th Ed. Mcgraw Hill, New York; 2015.

[8] Caliskan E, Cakiroglu Y, Sofuoglu K, Doger E, Akar ME, Ozkan SO. Effects of salpingectomy and antituberculosis treatments on fertility results in patients with genital tuberculosis. J Obstet Gynaecol Res 2014; 40: 2104–2109.

[9] Malhotra N, Sharma V, Bahadur A, Sharma JB, Roy KK, Kumar S. The effect of tuberculosis on ovarian reserve among women undergoing IVF in India. Int J Gynecol Obstet 2012; 117: 40–44.

[10] Pereira N, Pryor KP, Voskuilen-Gonzalez A, Lekovich JP, Elias RT, Spandorfer SD, et al. Ovarian response and in vitro fertilization outcomes after salpingectomy: does salpingectomy indication matter? J Minim Invasive Gynecol 2017; 24: 446–454.