International Journal of Reproductive BioMedicine

ISSN: 2476-3772

The latest discoveries in all areas of reproduction and reproductive technology.

 

CD52+ regulatory T cells and CD52-expressing sperms downregulated in couples with unexplained infertility: A case–control study

Published date: Jun 10 2020

Journal Title: International Journal of Reproductive BioMedicine

Issue title: International Journal of Reproductive BioMedicine (IJRM): Volume 18, Issue No. 5

Pages: 385–387

DOI: 10.18502/ijrm.v13i5.7159

Authors:

Mohammad RaeisiDepartment of Immunology, Shiraz University of Medical Sciences. Shiraz, Iran

Kurosh KalantarDepartment of Immunology, Shiraz University of Medical Sciences. Shiraz, Iran

Bahia Namavar JahromiDepartment of Obstetrics and Gynecology, Shiraz University of Medical Sciences. Shiraz, Iran; Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Behrouz Gharesi-FardGharesifb@sums.ac.irDepartment of Immunology, Shiraz University of Medical Sciences. Shiraz, Iran; Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract:

This is a Letter to the Editor and does not have an abstract.

References:

[1] Kamath MS, Bhattacharya S. Demographics of infertility and management of unexplained infertility. Best Pract Res Clin Obstet Gynaecol 2012; 26: 729–738.

[2] Kondelkova K, Vokurková D, Krejsek J, Borska L, Fiala Z, Ctirad A. Regulatory T cells (TREG) and their roles in immune system with respect to immunopathological disorders. Acta Medica (Hradec Kralove) 2010; 53: 73–77.

[3] Hasegawa A, Takenobu T, Kasumi H, Komori S, Koyama K. CD52 is synthesized in cumulus cells and secreted into the cumulus matrix during ovulation. Am J Reprod Immunol 2008; 60: 187–191.

[4] Robertson SA, Prins JR, Sharkey DJ, Moldenhauer LM. Seminal fluid and the generation of regulatory T cells for embryo implantation. Am J Reprod Immunol 2013; 69: 315–330.

[5] Guerin LR, Prins JR, Robertson SA. Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod Update 2009; 15: 517–535.

[6] Hosseini Teshnizi S, Ali-Hassanzadeh M, Gharesi-Fard B, Kabelitz D, Kalantar K. Influence of forkhead box protein 3 polymorphisms (rs2232365, rs3761548) with the outcome of pregnancy: A meta-analysis. J Cell Physiol 2019; 234, 9.

[7] Jin LP, Chen QY, Zhang T, Guo PF, Li DJ. The CD4+CD25 bright regulatory T cells and CTLA-4 expression in peripheral and decidual lymphocytes are down-regulated in human miscarriage. Clin Immunol 2009; 133: 402–410.

[8] Sasaki Y, Darmochwal-Kolarz D, Suzuki D, Sakai M, Ito M, Shima T, et al. Proportion of peripheral blood and decidual CD4(+) CD25(bright) regulatory T cells in pre-eclampsia. Clin Exp Immunol 2007; 149: 139–145.

[9] Watanabe T, Masuyama J, Sohma Y, Inazawa H, Horie K, Kojima K, et al. CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells. Clin Immunol 2006; 120: 247–259.

[10] Toh BH, Kyaw T, Tipping P, Bobik A. Immune regulation by CD52-expressing CD4 T cells. Cell Mol Immunol 2013; 10: 379–382.

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