International Journal of Reproductive BioMedicine

ISSN: 2476-3772

The latest discoveries in all areas of reproduction and reproductive technology.

 

Unexpected early pregnancy during myomectomy followed by successful term delivery: A case report

Published date: Oct 09 2024

Journal Title: International Journal of Reproductive BioMedicine

Issue title: International Journal of Reproductive BioMedicine (IJRM): Volume 22, Issue No. 8

Pages: 673–678

DOI: 10.18502/ijrm.v22i8.17242

Authors:

Nasrin SaharkhizPreventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mitra NematiPreventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Nazanin Hajizadehentative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Hajar Abbasihaabbasi65@gmail.comPreventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract:

Background: Leiomyoma, also known as uterine fibroid, is a non-malignant tumor originating from the uterus’s smooth muscles. It is the most common benign tumor in the female genital tract, exhibiting varying size and form that can distort the uterus’s shape. Uterine fibroids affect 2.7–10.7% of pregnant women and can lead to increased risks during pregnancy, such as miscarriage, placental abruption, preterm labor, and fetal malpresentation. Myomectomy is a surgical intervention for uterine fibroids, but it has drawbacks, including hemorrhage, fever, infection, ureter ligation, adhesive disorders, and unplanned hysterectomy.

Case Presentation: In this case report, we present a 32-yr-old woman with a large leiomyoma who underwent laparotomy myomectomy due to abdominal pain and heavy menstrual bleeding. 4 wk after the myomectomy, she was referred to the Obstetric Clinic of Ayatollah Taleghani hospital, Tehran, Iran complaining of delayed menstruation. Her beta-human chorionic gonadotropin test was positive. Ultrasound revealed a fetus with an estimated gestational age of 6 wk and 4 days. The pregnancy continued with no complications. At 38 wk of gestation, she underwent a cesarean section and delivered a healthy newborn.

Conclusion: This case report supports previous publications that have demonstrated the safety of myomectomy during pregnancy.

Key words: Leiomyoma, Pregnancy, Uterine myomectomy.

References:

[1] Coutinho LM, Assis WA, Spagnuolo-Souza A, Reis FM. Uterine fibroids and pregnancy: How do they affect each other? Reprod Sci 2022; 29: 2145–2151.

[2] Chill HH, Karavani G, Rachmani T, Dior U, Tadmor O, Shushan A. Growth pattern of uterine leiomyoma along pregnancy. BMC Womens Health 2019; 19: 100.

[3] Lou Zh, Huang Y, Li Sh, Luo Zh, Li Ch, Chu K, et al. Global, regional, and national time trends in incidence, prevalence, years lived with disability for uterine fibroids, 1990–2019: An age-period-cohort analysis for the global burden of disease 2019 study. BMC Public Health 2023; 23: 916.

[4] Spyropoulou K, Kosmas I, Tsakiridis I, Mamopoulos A, Kalogiannidis I, Athanasiadis A, et al. Myomectomy during pregnancy: A systematic review. Eur J Obstet Gynecol Reprod Biol 2020; 254: 15–24.

[5] Margueritte F, Adam C, Fauconnier A, Gauthier T. Time to conceive after myomectomy: Should we advise a minimum time interval? A systematic review. Reprod Biomed Online 2021; 43: 543–552.

[6] Kim H-S, Oh S-Y, Choi S-J, Park H-S, Cho G-J, Chung J-H, et al. Uterine rupture in pregnancies following myomectomy: A multicenter case series. Obstet Gynecol Sci 2016; 59: 454–462.

[7] Don EE, Mijatovic V, van Eekelen R, Huirne JAF. The effect of myomectomy on reproductive outcomes in patients with uterine fibroids: A retrospective cohort study. Reprod Biomed Online 2022; 45: 970–978.

[8] Cho H. Rupture of a myomectomy site in the third trimester of pregnancy after myomectomy, septoplasty and cesarean section: A case report. Case Rep Womens Health 2018; 19: e00066.

[9] Milazzo GN, Catalano A, Badia V, Mallozzi M, Caserta D. Myoma and myomectomy: Poor evidence concern in pregnancy. J Obstet Gynaecol Res 2017; 43: 1789–1804.

[10] Jhalta P, Negi SG, Sharma V. Successful myomectomy in early pregnancy for a large asymptomatic uterine myoma: Case report. Pan Afr Med J 2016; 24: 228.

[11] Allameh Z, Allameh T. Successful myomectomy in the second trimester of pregnancy. Adv Biomed Res 2019; 8: 60.

[12] Santos L, Vicente L, João Nunes M, Nery I, Caetano M, Assunção N. Myomectomy in early pregnancy: A case report. Gynecol Surg 2006; 3: 228–229.

[13] De Carolis S, Fatigante G, Ferrazzani S, Trivellini C, De Santis L, Mancuso S, et al. Uterine myomectomy in pregnant women. Fetal Diagn Ther 2001; 16: 116–119.

Download
HTML
Cite
Share
statistics

0 Abstract Views

10 PDF Downloads