Published date:Mar 24 2025

Journal Title: Dubai Medical Journal

Issue title: Dubai Medical Journal (DMJ): Volume 8, Issue 1

Pages:12 - 22

DOI: 10.18502/dmj.v8i1.18308

Zahra SadaghianiDepartment of Physical Therapy, Shahid Beheshti University of Medical Sciences, Tehran

Nahid Tahannahidta2431@gmail.comDepartment of Physical Therapy, Shahid Beheshti University of Medical Sciences, Tehran

Soheila GanjehDepartment of Physical Therapy, Shahid Beheshti University of Medical Sciences, Tehran

Alireza Akbarzadeh BaghbanProteomics Research Center, Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran

Ali KhoshdelDepartment of Physical Therapy, Shahid Beheshti University of Medical Sciences, Tehran

Ali ShoeibiDepartment of Neurology, Mashhad University of Medical Sciences, Mashhad

Introduction: Parkinson’s Disease (PD) is a disorder that causes both motor and nonmotor symptoms. While PD typically appears in older adults, it can also affect individuals in the later stages of middle age. Traditional drug therapies have side effects and diminishing returns. Exercise, particularly high-intensity programs like Lee Silverman Voice Treatment BIG (LSVT BIG), can enhance motor skills and overall quality of life by recalibrating the sensory system.

Method: This research included 40 individuals with PD, who were separated into a control group (standard physiotherapy) and an intervention group (physiotherapy + LSVT-BIG). Participants were from a local hospital, aged between 35 and 70, with stable medication and Montreal Cognitive Assessment (MoCA) scores > 20. Exclusions included active exercise programs and severe mental disorders. Participants were evaluated by an LSVT BIG-certified physical therapist and completed surveys on medical history and current issues. Tests included Timed Up & Go (TUG), TUG manual, and TUG cognitive. Both groups received 16 one-hour exercise sessions over 4 weeks. Statistical analyses included Kolmogorov-Smirnov for normality, independent t-test for baseline values, paired-sample t-test for within-group comparisons, and ANCOVA for post-test differences.

Results: Demographic and clinical attributes were consistently and normally distributed across groups (p > 0.05). Both groups demonstrated notable improvements across all outcomes (p < 0.05); however, the experimental group had a notably greater improvement in TUG cognitive scores in comparison to the control group (p < 0.05). No side effects occurred.

Discussion: TUG cognitive and manual tests highlighted LSVT-BIG’s effectiveness in enhancing dual-task performance.

Conclusion: Improvements in various TUG scores for individuals with PD indicate enhanced mobility and dual-task performance, which are crucial for daily activities and overall quality of life for individuals with PD.

Keywords: Parkinson’s disease, Lee Silverman Voice Treatment BIG, Timed Up & Go, high-intensity exercise

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