Dubai Medical Journal

ISSN: 2571-726X

Pioneering research in medicine, health sciences, nursing, pharmaceuticals, and laboratory work

Neuroendoscopic Lavage in Hydrocephalus with Ventricular Empyema: A Case Report

Published date: Nov 21 2024

Journal Title: Dubai Medical Journal

Issue title: Dubai Medical Journal (DMJ): Volume 7 Issue 2

Pages: 105–114

DOI: 10.18502/dmj.v7i2.17676

Authors:

Farhad Bal’afiffarblf@ub.ac.idNeurosurgery, Department of Surgery, Faculty of Medicine, Universitas Brawijaya / Dr. Saiful Anwar General Hospital, Malang, East Java

Tommy A NazwarNeurosurgery, Department of Surgery, Faculty of Medicine, Universitas Brawijaya / Dr. Saiful Anwar General Hospital, Malang, East Java

Donny W WardhanaNeurosurgery, Department of Surgery, Faculty of Medicine, Universitas Brawijaya / Dr. Saiful Anwar General Hospital, Malang, East Java

Oei Thomas SanjayaSpecialist Doctor Education Program, Department of Surgery Brawijaya University Malang Indonesia, Universitas Brawijaya / Dr. Saiful Anwar General Hospital, Malang, East Java

Keneysha Naomi MataniariMedicine Bachelor Study Program, Faculty of Medicine, Brawijaya University, Malang, East Java

Farahiyah Sharfina SaputriMedicine Bachelor Study Program, Faculty of Medicine, Brawijaya University, Malang, East Java

Liliana DewiMedicine Bachelor Study Program, Faculty of Medicine, Brawijaya University, Malang, East Java

Hisanifa ArifaniMedicine Bachelor Study Program, Faculty of Medicine, Brawijaya University, Malang, East Java

Ni Nyoman TrianaMedicine Bachelor Study Program, Faculty of Medicine, Brawijaya University, Malang, East Java

Mustofa ‎ Neurosurgery, Department of Surgery, Faculty of Medicine, Universitas Brawijaya / Dr. Saiful Anwar General Hospital, Malang, East Java

Abstract:

Introduction: Ventricular empyema, or pyogenic ventriculitis, is a severe condition characterized by pus accumulation in the cerebral ventricles due to intracranial infection, often caused by Gram-negative bacteria. Early diagnosis and treatment are crucial to prevent fatal neurological damage.

Case Report: A 3-month-old infant with severe hydrocephalus and ventricular empyema was admitted with symptoms of seizures, fever, and diarrhea. Initial examination showed decreased consciousness and significant leukocytosis. CT scans confirmed severe hydrocephalus and ventricular empyema. Despite resistance to standard antibiotics, neuroendoscopic lavage (NEL) and bilateral external ventricular drainage (EVD) were performed, leading to substantial improvement.

Discussion: The patient’s condition improved significantly post-surgery, with a decrease in leukocyte count and resolution of empyema as shown in follow-up imaging. This case demonstrates the efficacy of NEL in treating complex pediatric neurosurgical conditions.

Conclusion: NEL proves to be an effective treatment for intraventricular empyema in pediatric patients, improving clinical outcomes and reducing hospital stays. The success of this approach emphasizes the need for tailored neurosurgical interventions and regular follow-ups to ensure patient recovery and prevent recurrence.

Keywords: ventricular empyema, neuroendoscopic lavage (NEL), hydrocephalus, pediatric neurosurgery, gram-negative bacteria

References:

[1] Adhikari P, Antala D, Pyakuryal B, Muhammed A, Pudasainee P, Friedman H, et al. Community-acquired meningitis complicated by pyogenic ventriculitis: A case report. Cureus. 2022 Apr;14(4):e23907.

[2] Bajaj S. Newer antidiabetic drugs in Ramadan. J Pak Med Assoc. 2015 May;65(5 Suppl 1):S40–S43.

[3] Gaderer C, Schaumann A, Schulz M, Thomale UW. Neuroendoscopic lavage for the treatment of CSF infection with hydrocephalus in children. Childs Nerv Syst. 2018 Oct;34(10):1893–1903.

[4] Harris L, Munakomi S. Ventriculitis. StatPearls. StatPearls Publishing; 2023. http://www.ncbi.nlm.nih.gov/books/NBK544332/

[5] Honeyman SI, Boukas A, Jayamohan J, Magdum S. Neuroendoscopic lavage for the management of neonatal post-haemorrhagic hydrocephalus: A retrospective series. Childs Nerv Syst. 2022 Jan;38(1):115–121.

[6] Hong JT, Son BC, Sung JH, Kim IS, Yang SH, Lee SW, et al. Significance of diffusion-weighted imaging and apparent diffusion coefficient maps for the evaluation of pyogenic ventriculitis. Clin Neurol Neurosurg. 2008 Feb;110(2):137–144.

[7] Karvouniaris M, Brotis A, Tsiakos K, Palli E, Koulenti D. Current perspectives on the diagnosis and management of healthcare-associated ventriculitis and meningitis. Infect Drug Resist. 2022 Feb;15:697–721.

[8] Lang M, Habboub G, Moore NZ, Recinos VM, Mohammadi AM, Nagel S, et al. Neuroendoscopic evacuation of intraventricular empyema using a side-cutting aspiration device. J Clin Neurosci. 2018 Jan;47:323–327.

[9] Marinelli L, Trompetto C, Cocito L. Diffusion magnetic resonance imaging diagnostic relevance in pyogenic ventriculitis with an atypical presentation: a case report. BMC Res Notes. 2014 Mar;7(1):149.

[10] Schaumann A, Bührer C, Schulz M, Thomale UW. Neuroendoscopic surgery in neonates - indication and results over a 10-year practice. Childs Nerv Syst. 2021 Nov;37(11):3541–3548.

[11] Shah GS. Pyogenic ventriculitis and meningitis caused by Streptococcus acidominimus in humans: A case report. Am J Case Rep. 2018 Mar;19:329–334.

[12] Tandean S, Hendriansyah L, Djokomuljanto S, Saputra NA, Juliansen A, Valentina S, et al. Neuroendoscopic aspiration and lavage of intraventricular empyema following shunt infection in infants. Pan Afr Med J. 2018 Sep;31:15.

[13] Tirado-Caballero J, Rivero-Garvia M, Arteaga-Romero F, Herreria-Franco J, Lozano-Gonzalez Á, Marquez-Rivas J. Neuroendoscopic lavage for the management of posthemorrhagic hydrocephalus in preterm infants: Safety, effectivity, and lessons learned. J Neurosurg Pediatr. 2020 May;26(3):237–246.

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