Published date: Oct 30 2024

Journal Title: Dubai Medical Journal

Issue title: Dubai Medical Journal (DMJ): Volume 7 Issue 1

Pages: 16–23

DOI: 10.18502/dmj.v7i1.17496

Suleiman Daoudssdaoud@just.edu.joDepartment of Neurosurgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid

Rasha S. MustafaMD Intern, Ministry of Health, Irbid

Almutazballlah QablanMD Intern, Ministry of Health, Irbid

Yasmeen Jamal AlabdallatFaculty of Medicine, Hashemite University, Zarqa

Atef F. HullielFaculty of Medicine, Jordan University of Science and Technology, Irbid

Omar AhmadFaculty of Medicine, Jordan University of Science and Technology, Irbid

Adam M. AbdallahKing Abdullah University Hospital, Jordan University of Science and Technology, Irbid

Mohammad AlsharmanKing Abdullah University Hospital, Jordan University of Science and Technology, Irbid

Amer JaradatDepartment of Neurosurgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid

Sultan JarrarDepartment of Neurosurgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid

Mohammad A JamousKing Abdullah University Hospital, Jordan University of Science and Technology, Irbid

Mohemmed M. Al BarbarawiKing Abdullah University Hospital, Jordan University of Science and Technology, Irbid

Background: Traumatic brain injury (TBI) is one of the most common presentations to emergency departments and is associated with seizures carrying different significance at different stages following injury. The occurrence of seizures after head injury is a recognized complication of TBI and has been demonstrated to worsen functional outcomes significantly. Despite previous studies identifying various PTS risk factors, our understanding remains limited, particularly regarding familial seizure history.

Materials and Methods: A retrospective study was conducted at King Abdullah University Hospital (KAUH), Jordan, examining 1934 TBI cases from 2017 to 2023, identifying 118 patients with confirmed post-traumatic seizures.

Results: This study involved 118 TBI patients, aged between 2 and 86 years (median 21.5 years), with 74.6% male and 25.4% female. A family history of seizures was reported by 23.7% of patients. Intracerebral hemorrhage (ICH) (52.5%) and subarachnoid hemorrhage (SAH) (38.1%) were the predominant trauma types. Generalized tonicclonic (GTCs) seizures (69.5%) and focal seizures (30.5%) were observed post-TBI. Among 28 patients with a family history of seizures, no evidence of association was observed between the family history and post-traumatic seizure types (GTCs or focal seizures), this was confirmed by performing Chi-square tests (p = 0.9841) and logistic regression analysis (p = 0.79).

Conclusion: Our findings suggest that there is no evidence of the association between family history and post-traumatic seizure types, implying that a specialized approach for patients with positive family histories may not be warranted. Larger studies are recommended for further validation.

Keywords: TBI, PTS, seizure, epilepsy, family history

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