Advances in Applied Nano-Bio Technologies

Published date: Mar 20 2025

Journal Title: Advances in Applied Nano-Bio Technologies

Issue title: Advances in Applied Nano-Bio Technologies: Volume 6 Issue 1

Pages: 8 - 23

DOI: 10.18502/aanbt.v6i1.18639

Tahereh NaseriyehNanobiotechnology Department, Faculty of Innovative Science and Technology, Razi University Kermanshah

Fereshteh AbdiDepartment of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz

Zeynab AhmadifardSchool of Pharmacy, Lorestan University of Medical Sciences, Khorramabad

Danial Kahrizid.kahrizi@cellmolbiol.orgAgricultural Biotechnology Department, Faculty of Agriculture, Tarbiat Modares University, Tehran

Hydrogels, which are porous three-dimensional polymers with a high capacity for water absorption, have a wide range of applications in biomedical engineering, particularly in wound healing. However, limitations such as low mechanical strength and the absence of controlled drug release hinder their effectiveness. Incorporating nanoparticles (NPs) into hydrogels presents an effective solution to enhance these properties. NPs not only serve as drug carriers, improving drug stability and enabling controlled release, but certain types, such as silver (Ag), gold, and silica NPs, also augment the anti-inflammatory and antibacterial properties of hydrogels. Additionally, metal NPs, including Ag, copper, and zinc oxide (ZnO), contribute to reducing the risk of infection and accelerating the wound healing process through mechanisms such as the production of reactive oxygen species (ROS) and the inhibition of microbial proliferation. Furthermore, the incorporation of nanomaterials, such as carbon nanotubes and silica v, enhances the strength, flexibility, and durability of hydrogels in physiological environments. These advancements have positioned nanoparticle-reinforced hydrogels as a promising option in the fields of regenerative medicine and tissue engineering.

Keywords: hydrogel, nanoparticles, wound healing

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