Advances in Applied Nano-Bio Technologies

Published date: Mar 20 2025

Journal Title: Advances in Applied Nano-Bio Technologies

Issue title: Advances in Applied Nano-Bio Technologies: Volume 6 Issue 1

Pages: 61 - 72

DOI: 10.18502/aanbt.v6i1.18263

Esmat Azizipouresmatazizipour71@yahoo.comDepartment of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz

Reza Yarahmadiray1406yar@gmail.comDepartment of Molecular Medicine, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord

There is always an urgent need for proper bone tissue substitutes with a biomimetic approach. Natural hydrogel composites containing bioceramics are promising scaffolds for bone tissue regeneration as they simulate the extracellular matrices and appropriate performance. Among biopolymers, collagen can resemble the fibrillar structure of bone extracellular matrix. However, collagen extraction is costly, therefore, gelatin as a derivate of collagen can be a reasonable alternative. Regarding the poor strength of polymeric hydrogels, the company of bioceramics like bioactive glasses provided bone firmness and stable bonds with host tissues. This article aims to provide a comprehensive overview of the application of collagen and gelatin hydrogels containing various types of bioactive glasses as scaffolds for bone tissue regeneration.

Keywords: bone tissue engineering, hydrogels, collagen, gelatin, bioactive glass, scaffold

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