Sudan Journal of Medical Sciences

ISSN: 1858-5051

High-impact research on the latest developments in medicine and healthcare across MENA and Africa

Presentation of Invasive Fungal Rhinosinusitis in Sudanese Children: A Report of Four Cases

Published date: Jun 28 2018

Journal Title: Sudan Journal of Medical Sciences

Issue title: Sudan JMS: Volume 13 (2018), Issue No. 2

Pages: 125-132

DOI: 10.18502/sjms.v13i2.2643

Authors:

Sharfi Ahmed - doctorsharfi@gmail.com

Khalid Awad Elseed

Abstract:

Fungal rhinosinusitis (FS) is considered as a disease spectrum that ranges from allergic fungal sinusitis (AFS) and chronic fungal rhinosinusitis (CFS) to invasive fungal rhinosinusitis (IFS) invading the orbit, Dura, and intra-cranium. Fungal rhinosinusitis is a common disease in Sudan.

Objective: To present four rare cases of Invasive
Fungal Rhinosinusitis in Sudanese children presented with orbital extension.

Patients and Method: The authors have reported four cases of children in the age range of 9–11 years, two girls and two boys; they were presented with invasive fungal rhinosinusitis in Africa ENT hospital (Sudan) during the period from September 2015 to August 2017. Patients’ diagnosis was made by endoscopic examination, CT, and MRI,
and it was confirmed by tissue biopsy.

Results: Patients’ age range was 9–11 years, two girls and two boys. The unilateral disease was the commonest type. An orbital extension was detected in all cases on CT and MRI. No intracranial extension was detected. Aspergillus flavus was the most responsible agent detected in all the four
cases.

Conclusion: Fungal rhinosinusitis (FS) is a common disease in adult Sudanese patients but rarely affects children. It is mainly caused by Aspergillus species. The disease is extensive and can be associated with orbital and intracranial complications.

References:

1] Ponikau JU, Sherris DA, Kern EB, Homburger HA, Frigas E, GaffeyTA, et al. The diagnosis and incidence of allergic fungal sinusitis. Mayo ClinProc 1999;74: 877-84

[2] Hora JE. Primary Aspergillosis of the Paranasal Sinuses and associated areas. laryng oscope 1965;75:768-73.

[3] Wright RE. Two cases of granuloma invading the orbit due to Aspergillosis.Br J ophthal 1972;12:545-59.

[4] Deshazoetal.classification of funal sinusitis. Rhinology 1997;39:283-4.

[5] DeShazoetal .A new classification and diagnostic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 1997.123:1181-1188.

[6] Rudwan MA, Sheikh HA,. Aspergilloma of the Paranasal Sinuses is a common cause of unilateral proptosis in Sudan. clin Radiol 1976;27: 497-02.

[7] Sandison AT,Gentles JC, Davidson CM,Banko M. Aspergilloma of the Paranasal Sinuses and orbit in nothern Sudan. Sabourndia 1969;6:57-69.

[8] Bella V, Malik OA , . Mahgoub EL, El hassanMA,etal. Further observation on the Primary Paranasal Sinuses Aspergillus granuloma in Sudan. Trop med hyg1973;22:765-772.

[9] Yagi HI, Gumma SA etal.Nasosinuses Aspergillosis in Sudanese Patients. clinical features, pathology, diagnosis and treatment. The J of oto and lary. 1999;28.2:90:94.

[10] Stammberger H, etal. Aspergillosis of the paranasalsinuses. AnnOto Rhino Laryngo 1985 .94(119):1-11.

[11] Milosev B, Mahgoub EL S,etal. Primary Aspergilloma of the Paranasal Sinuses in Sudan.Br J surgery 1969;56:132-7.

[12] Mahgoub EL S. Mycological and Serological studies on Aspergillousflavus isolated from the Paranasal Sinuses Aspergilloma.Trop med hyg 1971; 74:168-75.

[13] Bent J, Kuhn FA. Diagnosis of allergic fungal sinusitis.Otolaryngol Head Neck Surg . 1994; 111:580-588.

[14] Mahgoub EL S. El Hassan MA. pulmonary Aspergilloma caused by Aspergillousflavus 1975. ThoraxJ ;27 233-37.

[15] Dawalatly EE, Amin JT, Elhassan AY etal. Primary Paranasal Sinuses Aspergillosis in SoudiaArabia . Trop med J . I988 Jul .40(3): 247-50.

[16] Thakar A, Sarkar C, Dhiwakar M, Bahadur S, Dahiya S. Allergic fungal sinusitis:expanding the clinicopathologic spectrum. Otolaryngol Head Neck Surg . 2004;130:209-216.

[17] Katzenstein AL, Sale SR, Greenberger PA. Allergic Aspergillus sinusitis: a newly recognized form of sinusitis. J Allergy ClinImmunol . 1983;72:89-93.

[18] Schubert MS. Allergic fungal sinusitis. OtolaryngolClin North Am . 2004;37:301-326.

[19] Sharfi AO, ELmustafa. Clinical features of fungal rhinosinusitis in Sudan.PAJR , Vol.3, No. 1, March, 2013.

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