Published date: Dec 05 2018

Journal Title: KnE Life Sciences

Issue title: The 2nd International Conference on Hospital Administration (The 2nd ICHA)

Pages: 161–171

DOI: 10.18502/kls.v4i9.3568

A Ramadhona

S Supriyanto

S Martinisanti-m@fkm.unair.ac.id

The background of this study is the increasing number of leprosy reaction incidence treated at Sumberglagah Leprosy Hospital from 6.76% to 10.3% in September 2016. The purpose of this study is to generate recommendations for leprosy reaction prevention efforts based on risk factor analysis at Sumberglagah Leprosy Hospital of Mojokerto. The method of research was an observational analytic study with crosssectional design. The sampling technique applied in this study was total sampling, meaning that all the sample cases became respondent consisting of patients coming to Sumberglagah Leprosy Hospital Mojokerto from February 13, 2017 to April 12, 2017, not new patients, not yet released from control, and willing to became respondent.
Based on these criteria, we got 43 respondents. Data collection techniques applied in this study were interviews with questionnaires, medical record review, and focal group discussions. The results show four variables of individual factors that influence the incidence of leprosy reaction, namely, leprosy type (p = 0.022 and beta = –0.997), comorbid infections (p = 0.023 and beta = 0.319), physical stress (p = 0.001 and beta
= –0.431), and behavioral stress (p = 0.016 and beta = 0.393). The environmental factor influencing the incidence of leprosy reaction constitutes one variable of selfstigma (p = 0.025 and beta = –0.226). While for health service factor, there are two variables that influenced the incidence of leprosy reaction, that is, compliance in
treatment of MDT (multidrug therapy) (p = 0.021 and beta = –0.349) and counseling by officer (p = 0.011 and beta = –0.247). Recommendations of preventions effort of leprosy reactions based on risk factor analysis can be carried out through primary prevention efforts (health promotion and counseling) and secondary prevention
efforts (early diagnosis and prompt treatment and disability limitation). The tertiary prevention effort (rehabilitation) may include group therapy and occupational therapy.

Keywords: prevention effort, leprosy reaction, risk factor, leprosy hospital

[1] Kosasih, A., et al. (2005). Kusta (Ilmu Penyakit Kulit Kelamin, edisi IV) , pp. 73–88. Jakarta: FKUI.


[2] Ramaswari, N. P. A. Y. (2015). Masalah Reaksi Reversal dan Eritema Nodosum Leprosum pada Penyakit Kusta. CDK, vol. 42, pp. 654–657.


[3] Ditjen P2PL. (2012). Buku Pedoman Nasional Pemberantasan Penyakit Kusta (Cetakan XVIII), pp. 1–138. Jakarta: Kemenkes RI.


[4] Supriyanto, Stefanus, and Djohan, A. J. (2011). Metodologi Riset Bisnis dan Kesehatan. Banjarmasin Post Group. Banjarmasin, Kalimantan: PT. Grafika Wangi Kalimantan.


[5] Woodard, Phillip P. (September 2015). Four Key Determinants of Health - The Blum Model, vol. 2.


[6] Udi, Mas, M. A., Soebono, et al. (2015). Faktor Risiko Kejadian Reaksi Kusta di Rumah Sakit Kusta Kediri. Yogyakarta: Universitas Gadjah Mada.


[7] Swarth, J. (2001). Stress dan Nutrisi. Jakarta: Bumi Aksara.


[8] Soedarjatmi. (2009). Faktor-faktor yang melatarbelakangi persepsi penderita terhadap Stigma penyakit Kusta. Jurnal Promosi Kesehatan Indonesia, vol. 4, no. 1.


[9] Smet, B. (1994). Psikologi Kesehatan. Jakarta: Gramedia.


[10] Sharma, N., Patel, N. M., and Mahakal, N. (2013). Lepra reactions – A clinical and histopathological study. International Journal of Scientific Research, vol. 2, no. 1, pp. 185–186.


[11] Schollard, D. M., et al. (1994). Epidemiologic characteristics of leprosy reactions. International Journal of Leprosy, vol. 64, no. 2, pp. 559–565.


[12] Salim, P. (1996). The Contemporary English-Indonesia Dictionary (seventh edition). Jakarta: Modern English Press.


[13] Ranque, B., et al. (2004). Age is an Important Risk Faktor for Onset and sequele of Reversal Reactions in Vietnamese Patients with Leprosy, pp. 33–39.


[14] Prawoto. (2008). Faktor-Faktor Risiko yang Berpengaruh terhadap terjadinya Reaksi Kusta. Semarang: Magister Epidemiologi, Program Pascasarjana, Universitas Diponegoro.


[15] Pagolori. (2003). Analisis Faktor Risiko Reaksi sesudah Pengobatan MDT pada penderita Kusta di Kabupaten Gowa tahun 2002, pp. 1–2. Makasar: FKM Universitas Hasanudin.


[16] Nery, J. A. da C., et al. (2013). Understanding the type 1 reactional state for early diagnosis and treatment: A way to avoid disability in leprosy. An Bras Dermatol, vol. 88, no. 5, pp. 787–792.


[17] Mongi, R. A. (2012). Gambaran Persepsi Penderita tentang Penyakit Kusta dan Dukungan Keluarga pada Penderita Kusta di Kota Manado. Manado: FKM Universitas Sam Ratulangi.


[18] Mondal, A., et al. (2015). A clinicodemographic study of lepra reaction in patients attending dermatology department of a tertiary care hospital in Eastern India. Journal of Pakistan Association of Dermatologists, vol. 25, no. 4, pp. 252–258.


[19] Mastrangelo, G., et al. (2008). How to prevent immunological reactions in leprosy patients and interrupt transmission of Mycobacterium leprae to healthy subjects: Two hypotheses. Medical Hypotheses, vol. 71, pp. 551–563.


[20] Machado, Ribeiro, F. and Shoenfeld, Y. (2015). Leprosy and Autoimmunity. Infection and Autoimmunity, pp. 583–597. Brazil: Elsevier B.V.


[21] Kumar, et al. (2004). Epidemiological Characteristic of Leprosy Reactions: 15 Year Experience From North India, pp. 1–2.


[22] Kozier, Barbara, J., et al. (2004). Fundamentals of Nursing: Concepts, Process and Practice (sixth edition). New Jersey: Pearson Prentice Hall.


[23] Karen, G., Barbara, K., Rimer, et al. (2008). Health Behavior and Health Education (fourth edition). San Franscisco, USA: John Wiley and Sons, Inc.


[24] Julan, T. ( January 28, 2015). Jawa Timur Kantong Kusta di Indonesia. Jakarta: Koran Sindo, Rabu.


[25] Joshi, P. L. (2009). Training Manual for Medical Officers. Nirman Bhawan, New Delhi: National Leprosy Eradication Programme, Directorate General of Health Services, Ministry of Health and Family Welfare.


[26] Irsan, Q., Abdurrachman, B., and Raharjo, W. (2014). Kejadian Reaksi Kusta di Puskesmas Kota Pontianak. Pontianak: FK Universitas Tanjungpura.


[27] Dinkes Provinsi Jatim. (2015). Profil Kesehatan Provinsi Jawa Timur 2014. Surabaya: Dinas Kesehatan Provinsi Jawa Timur.


[28] Dayakisni, T. and Hudaniah. (2003). Psikologi Sosial (Edisi Revisi). Malang: UMMPress.


[29] Christian. (2005). Jinakkan Stress. Bandung: Nexx Media.


[30] Khawas, I. B. and Lucas, S. B. (1994). Reaction in Leprosy: An Epidemiological Study of Patients in Nepal; van Brakel, W. H. (1994). Leprosy Review, vol. 65, pp. 190–193.


[31] Blum, H. L. (1983). Expanding Health Horizon: From a General Systems Concept of Health to a National Health Policy. Oakland, CA: Third Party Publishing Company.


[32] Ather, A. and Katz, D. L. (2015). Disease prevention and health promotion. 49 (503), American Journal of Preventive Medicine, vol. November 01, pp. S230–S240.


[33] Ariyani, N. and Wahjuni, C. U. (2011). Faktor yang Berhubungan dengan Kejadian Reaksi Kusta di Rumah Sakit kusta Sumberglagah Mojokerto. Surabaya: FKM Universitas Airlangga.


[34] Antunes, E., Douglas, et al. (2013). Identification of Clinical, Epidemiological and Laboratory Risk Factors for Leprosy Reactions during and after multidrug therapy. Memórias do Instituto Oswaldo Cruz, Rio De Janeiro, vol. 108, no. 7.


[35] Adhikari, B., et al. (2013). Risk factors of stigma related to leprosy – A systemic review. JMMIHS, vol. 1, no. 2, pp. 3–11.


[36] Pusat Pelatihan Kusta Nasional. (2012). Modul Epidemiologi dan Program Pemberantasan Penyakit Kusta. Makasar: Kemenkes RI.