KnE Life Sciences

ISSN: 2413-0877

The latest conference proceedings on life sciences, medicine and pharmacology.

ANTICANCER AND ANTIAGGREGATION OF SEAWEED EXTRACT

Published date: Feb 01 2015

Journal Title: KnE Life Sciences

Issue title: International Symposium on Aquatic Product Processing (ISAPPROSH) 2013

Pages: 120-124

DOI: 10.18502/kls.v1i0.95

Authors:

Astuti Lamidastuti4@yahoo.comCentre of Applied Technology of Health and Clinical Epidemiology

K KomariCentre of Biomedical and Basic Technology of Health

Abstract:

Exploration of seaweed potential as sources of bioactive compounts were studied and found two type seaweeds from in Bali such as Caulerpa rasemosa and Gracillaria sp had potential as food suplements and prepared and consumed as food. These seaweeds were used as vegetables in daily diet as side dishes or can be consumed alone. Their bioactive components of these seaweeds were explored for degenerative diseases. Gracillaria sp or bukung hijau were extracted with different solvents and tested qualitatively for possible bioactive component. as anti cancer agents and anti platelet aggregations were performed in vitro. Using cancer cell of mice (C3H) and New Zealang Rabbits Platelet. The results showed that anti cancer growth of the extract was 7th fraction of the extract with 78% activities and LD50 was 0.1 ppm. The anti platelets aggregation optimum of the extract was 13.2%. The formulation of food supplement from these seaweed may benefit to produce functional food related to health.

Keywords: seaweed extract, anti-cancer, anti platelet aggregation

 

References:

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Ito K, Hori K 1989. Seaweed: Chemical composition and potential uses. Food Rev.Int.5:101-144
Komari. 1997. Bioactive compounds of macroalgae for inhibitor of platelet aggregation. Presented at Indonesian Biotech. Conf. Jakarta, 17-19 June 1997
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