Published date: Apr 05 2021

Journal Title: KnE Life Sciences

Issue title: DonAgro: International Research Conference on Challenges and Advances in Farming, Food Manufacturing, Agricultural Research and Education

Pages: 342–349

DOI: 10.18502/kls.v0i0.8965

Yulia Luschai lyuliya1989@bk.ruAltai State Agrarian University, Russian Federation, Altai Territory, city of Barnaul

Olga DutovaAltai State Agrarian University, Russian Federation, Altai Territory, city of Barnaul

Elena ShaganovaAltai State Agrarian University, Russian Federation, Altai Territory, city of Barnaul

Irina PleshakovaAltai State Agrarian University, Russian Federation, Altai Territory, city of Barnaul

Elena MashkinaAltai State Agrarian University, Russian Federation, Altai Territory, city of Barnaul

The Altai territory is an agricultural region; it is a biogeochemical province deficient in iodine. We conducted a study of metabolic disorders in cows that had hypofunction of the thyroid gland. Our research is devoted to the expediency of a single use of the drug “Kayod” administered in the form of a subcutaneous implant in order to normalize the therapeutic status of animals suffering from a chronic lack of iodine in their diet. The purpose of this work is to justify not only the use of the preparation “Kayod” in animals kept in the biogeochemical provinces deficient in iodine, but also the use of tablets administered through a subcutaneous implant. We found a significant increase in the amount of hemoglobin and a decrease in the number of white blood cells in the blood of animals after the use of “Kayod”, and in the second experimental group, these indicators were slightly higher than in the first one. Indicators of the level of total protein and reserve alkalinity of blood were within the limits of physiological norms, but in the experimental groups they were slightly higher than in the control group. The level of total calcium and carotene in the blood of animals in the experimental groups, especially the second, significantly exceeded the level of the same substances in the blood of the animals in the control group. However, the level of inorganic phosphorus tended to decrease. The level of glucose in the blood of cows in the experimental group increased significantly more than in the blood of cows in the control group. This increase was particularly significant in the blood of animals in the second experimental group. When the preparation “Kayod” was used in the form of a subcutaneous implant, there were no clinical signs of hypothyroidism in the cows of the first experimental group after nine weeks. In the cows of the second experimental group, the condition of the cows returned to normal after six weeks.

Keywords: Cows, iodine, hypothyroidism, implant, “Kayod

[1] Bitueva, E. B., Zhamsaranova, S. D. and Antipova, L. V. (2007). Evaluation of the Effectiveness of Using Iodine-Containing Biologically Active Additives to Food in the Experiment. Questions of Nutrition, vol. 25 (2), pp. 57-59.

[2] Zhamsaranova, S. D., Anudar, D. and Ryabusheva, A.V. (2011). Evaluation of the Endocrine Status of Experimental Animals when Introducing a Complex Containing Bound Forms of Iodine and Selenium against the Background of Experimental Hypothyroidism. Microelements in Medicine, vol. 28 (3-4), pp. 70-72.

[3] Kapustina, Y. A. and Zhamsaranova, S. D. (2009). Evaluation of Functional State of the Thyroid Gland in an Experiment. Bulletin of the East Siberian Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences, vol. 2, issue 66, pp. 106-108.

[4] Kovzov, V. V. (1998). Treatment of Calves with Enzootic Goiter, with Correction of the Immune Status. Scientific Notes of the Educational Institution Vitebsk Order of the Badge of Honor State Academy of Veterinary Medicine, vol. 43 (1), pp. 42-45.

[5] Mikhailichenko, V. Y. and Vasilianskaia, O. V. (2013). Pathophysiological Aspects of Hypothyroidism in the Experiment. General Pathology and Pathological Physiology, vol. 53 (3), pp. 58-62.

[6] Abusuev, S. A. (2002). Iodine Deficiency and Hypothyroidism in Dagestan. In Materials of the Scientific Conference “Topical Issues of Thyroid Diseases”. Moscow: publishing house Mediasfera

[7] Baimatov, V. N., Ismagilova, E. R. and Vasiaev, V. A. (2005). The Health Status of Cattle in the Zone of the Biogeochemical Province. Veterinary Science, vol. 32 (1), pp. 42-45.

[8] Blagosklonnaya, Y. V. (2007). Endocrinology. Saint Petersburg: SpetsLit.

[9] Veldanova, M. V. (2001). Problems of Iodine Deficiency from a Doctor’s Point of View. Issues of Endocrinology, vol. 47 (5), pp. 34.

[10] Volvachev, V. N. (2000). Hypothyroidism and its Impact on the Quality of Livestock Products. Krasnoyarsk: Krasnoyarsk State Agricultural University.

[11] Voronina, E. N. (2008). The Influence of Environmental Factors on the Physiological Functions of the Body and the Activity of Functional Systems in Calves in the Biogeochemical Province of the South Urals. Veterinary Pathology, vol. 2, issue 25, pp. 35-37.

[12] Gamaiunov, V. M. (2007). The Biological Role of Trace Elements in Animal Life. Practician, vol. 75 (1), pp. 46-49.

[13] Gusakov, V. K. (2004). Influence of Iodine-Containing Preparations on Blood Parameters of Sows and Piglets. Veterinary Science, vol. 10 (1), pp. 54-55.

[14] Dedov, I. I. (2001). Strategy for the Elimination of Iodine Deficiency Diseases in the Russian Federation. Issues of Endocrinology, vol. 47, pp. 3-12.

[15] Denisenko, V. N. and Abramov, P. N. (2006). Correction of Iodine Deficiency in Cattle in the Moscow Region. Veterinary Science, vol. 34 (3), pp. 47-50.