Published date: Mar 25 2019

Journal Title: KnE Life Sciences

Issue title: The 1st International Conference on Health, Technology and Life Sciences (ICO-HELICS)

Pages: 266–273

DOI: 10.18502/kls.v4i12.4182

S Widhiatisuciwidhiati@staff.uns.ac.id

R D Utami

D Zulfikar

A Kusumawardani

E Yustin

Triasari .

K Dewi

N Mulianto

P Mawardi

I Julianto

Aplasia cutis congenital (ACC) in lower legs is a rare disease with the absence of the skin, which commonly localized, widespread or scarred at birth. The exact pathophysiology remains unclear, and varicella infection may have essential roles in the aetiologies. Wound healing can be accelerated by using Human Dermal Papillae
Conditioned Medium (HDPCM) which has multi-lineage potential differentiation and releases many growth factors. This paper reports the possibility of using human dermal papillae conditioned media to speed up the wound healing process. A 4 days old baby boy presented with ulcers on his both knees since birth and had no history of birth trauma. The mother had varicella infection during the 2

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