Published date: Dec 27 2022

Journal Title: KnE Life Sciences

Issue title: Science and Technology Research Symposium (SIRES)

Pages: 273–281

DOI: 10.18502/kls.v7i5.12536

I. T. Maulanaindra.topik@gmail.comNatural Product of Pharmacy Science Group, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Bandung, Indonesia

F. DarusmanPhamacology Science Group, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Bandung, Indonesia

L. MulqiePharmaceytical Science Group, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Bandung, Indonesia

S. E. PrianiPharmaceytical Science Group, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Bandung, Indonesia

E. N. MaulidyaPharmaceytical Science Group, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Bandung, Indonesia

Ziziphus spina-christi L. or Jujube, is a plant that has many health benefits, containing metabolite compounds that act as an antibacterial agent such as alkaloids, flavonoids, saponins, tannins, and polyphenols. This study aimed to make a natural antiseptic liquid from Ziziphus spina-christi L. leaf extract used in Islamic Bathing Procedures for a corpse. The stages of this research included extraction, an assay of the extract’s antiseptic activity using the agar well diffusion method, formulating the antiseptic liquid, evaluating the antiseptic liquid, and examining the antiseptic properties of the liquid. Jujube leaf extract with a concentration of 10% was proven to have the best antibiotic properties with a very strong inhibition zone category. Antiseptic liquid formulations include extracts, DMDM hydantoin, Triethanolamine, and Aqua rose. The organoleptic evaluation results of liquid antiseptic were in the form of a homogeneous concentrate liquid, brown with a rose aroma, pH 9.048, the density of 1.020 g/mL, viscosity of 5.60 m.Pas, and 0.7 cm high foam with high foam stability of 83.33%. The antiseptic test results showed that the antiseptic solution was able to inhibit the growth of Escherichia coli, Staphylococcus epidermidis, and Candida albicans ranging from strong to very strong inhibition zone diameters, 17.35 mm, 21.10 mm, and 19.95 mm, respectively.

Keywords: antiseptic, antimicrobial, corpse bathing, jujube leaf (ziziphus spina christi L.)

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