Published date: Dec 27 2022

Journal Title: KnE Life Sciences

Issue title: Science and Technology Research Symposium (SIRES)

Pages: 129–139

DOI: 10.18502/kls.v7i5.12519

H. S. Yuwonohsyabc47@gmail.comPostgraduate Program, Faculty of Medicine, Universitas Islam Bandung, Bandung, Indonesia

M. PutriDepartment of Biochemistry, Nutrition and Biomolecular, Faculty of Medicine, Universitas Islam Bandung, Bandung, Indonesia

W. PurbaningsihDepartment of Histology, Faculty of Medicine, Universitas Islam Bandung, Bandung, Indonesia

N. M. MarsyaUndergraduate Program, Faculty of Medicine, Universitas Islam Bandung, Bandung, Indonesia

S. A. SumantriUndergraduate Program, Faculty of Medicine, Universitas Islam Bandung, Bandung, Indonesia

Coffee grounds have been used to dress wounds for more than 100 years, with excellent results. The wound heals with an acceptable scar. This study aims to compare coffee extract to neomycin-bacitracin in cell migration. Compared to the antibiotic neomycin-bacitracin powder group and control group in scar tissue formation, the Robusta coffee powder extract measured positively on Transforming Growth Factor and Basic Fibroblast Growth Factor markers. This study emphasizes the ability of coffee to heal wounds without causing excessive scarring. Coffee is proven to have better wound healing capabilities than Neomycin-Bacitracin.

Keywords: coffee grounds, fibroblast cell-line, Transforming Growth Factor, basic Fibroblast Growth Factor

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