Published date: Dec 27 2022

Journal Title: KnE Life Sciences

Issue title: Science and Technology Research Symposium (SIRES)

Pages: 72–78

DOI: 10.18502/kls.v7i5.12510

D. Setiapriagungd2setiapriagung@gmail.comRadiology Department, Al-Islam Hospital, Bandung, Indonesia

C. Tresnasari Physiology Department, Medical Faculty Universitas Islam Bandung, Bandung, Indonesia

T. WidiyantoInternal Medicine Department, Al-Islam Hospital, Bandung, Indonesia

F. A. Yulianto Public Health Department, Medical Faculty, Universitas Islam Bandung, Bandung, Indonesia

T. Respati Public Health Department, Medical Faculty, Universitas Islam Bandung, Bandung, Indonesia

L. YuniartiBiochemistry Department, Medical Faculty, Universitas Islam Bandung, Bandung, Indonesia

COVID-19 attacks the respiratory system, especially the lung. Therefore, it is necessary to examine the lung radiology of COVID-19 patients to plan the best treatment. This study aimed to describe radiological features in deceased patients at a hospital in Bandung, Indonesia. This study uses secondary data from the medical records of deceased COVID-19 patients from December 2020 to February 2021. Amongst the 129 patients who died whilst hospitalized, their chest X-ray showed pneumonia consisting of ground glass opacities (GGO) and consolidated lesions. The mean distribution of lesions was unilateral in 3 (2.33%) and bilateral in 126 (97.67%). In comparison, peripheral lesions were found in 80 (62.02%), and peripheral-medial lesions were found in 49 (37.98%). The mean of the lesions affecting the upper lung fields were 2.63 (DS 1.19), the middle lung fields were 4.39 (DS 1.82), and the lower lung fields were 4.88 (DS 1.53). When admitted to the isolation ward, the average Brixia score on a chest X-ray was 11.9 (95% CI 12.74; 11.16). In conclusion, the radiological features of COVID-19 patients who died under treatment showed ground glass opacities and consolidated lesions. The predominant distribution was on bilateral, peripheral, and lower lesions with a high Brixia score.

Keywords: COVID-19, mortality, the brixia score.

[1] Kementerian KR. Pedoman Pencegahan Dan Pengendalian Corona Virus Disease (Covid-19). 2020.

[2] Keputusan Presiden Republik Indonesia No 12 Tahun 2020 Tentang Penetapan Bencana Nonalam Penyebaran Corona Virus Disease 2019. Indonesia: Sebagai Bencana Nasional; 2020.

[3] Sánchez-Oro R, Torres Nuez J, Martínez-Sanz G. Radiological findings for diagnosis of SARS-CoV-2 pneumonia (COVID-19). Med Clín (Engl Ed). 2020 Jul;155(1):36–40.

[4] Balbi M, Caroli A, Corsi A, Milanese G, Surace A, Di Marco F, et al. Chest X-ray for predicting mortality and the need for ventilatory support in COVID-19 patients presenting to the emergency department. Eur Radiol. 2021 Apr;31(4):1999–2012.

[5] da Rosa Mesquita R, Francelino Silva Junior LC, Santos Santana FM, Farias de Oliveira T, Campos Alcântara R, Monteiro Arnozo G, et al. Clinical manifestations of COVID-19 in the general population: systematic review. Wien Klin Wochenschr. 2021 Apr;133(7-8):377–82.

[6] Elezkurtaj S, Greuel S, Ihlow J, Michaelis EG, Bischoff P, Kunze CA, et al. Causes of death and comorbidities in hospitalized patients with COVID-19. Sci Rep. 2021;11(1):1– 9.

[7] Rubin GD, Ryerson CJ, Haramati LB, Sverzellati N, Kanne JP, Raoof S, et al. The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Radiology. 2020 Jul;296(1):172–80.

[8] World Health Organization Guidance Note. Use of chest imaging in COVID-19: a rapid advice guide. 2020. 56.

[9] Sarkodie BD, Osei-Poku K, Brakohiapa E. Med Case Rep (Wilmington). 2020;6(2):10−2.

[10] Borghesi A, Maroldi R. COVID-19 outbreak in Italy: experimental chest X-ray scoring system for quantifying and monitoring disease progression. Radiol Med (Torino). 2020 May;125(5):509–513.

[11] Setiawati R, Widyoningroem A, Handarini T, Hayati F, Basja AT, Putri AR, et al. Modified Chest X-Ray Scoring System in Evaluating Severity of COVID-19 Patient in Dr. Soetomo General Hospital Surabaya, Indonesia. Int J Gen Med. 2021 Jun;14:2407–2412.

[12] Smith DL, Grenier JP, Batte C, Spieler B. A Characteristic Chest Radiographic Pattern in the Setting of the COVID-19 Pandemic. Radiol Cardiothorac Imaging. 2020 Sep;2(5):e200280.

[13] Cozzi D, Albanesi M, Cavigli E, Moroni C, Bindi A, Luvarà S, et al. Chest X-ray in new Coronavirus Disease 2019 (COVID-19) infection: findings and correlation with clinical outcome. Radiol Med (Torino). 2020 Aug;125(8):730–7.

[14] Chen H, Ai L, Lu H, Li H. Clinical and imaging features of COVID-19. Radiol Infect Dis. 2020 Jun;7(2):43–50.

[15] Smithuis R, Delden OV.Chest X-Ray: Basic Interpretation. From https://radiologyassistant.nl. 2013.

[16] Attaway AH, Scheraga RG, Bhimraj A, Biehl M, Hatipoğlu U. BMJ. 2021;372.

[17] Shang J, Ye G, Shi K, Wan Y, Luo C, Aihara H, et al. Structural basis of receptor recognition by SARS-CoV-2. Nature. 2020 May;581(7807):221–4.

[18] Wu YC, Chen CS, Chan YJ. The outbreak of COVID-19: an overview. J Chin Med Assoc. 2020 Mar;83(3):217–20.

[19] Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: A review. Clin Immunol. 2020 Jun;215.

[20] Haseli S, Khalili N, Bakhshayeshkaram M, Taheri MS, Moharramzad Y. Arch Acad Emerg Med. 2020;8.

[21] Wong HY, Lam HY, Fong AH, Leung ST, Chin TW, Lo CS, et al. Frequency and Distribution of Chest Radiographic Findings in Patients Positive for COVID-19. Radiology. 2020 Aug;296(2):72–78