KnE Life Sciences
ISSN: 2413-0877
The latest conference proceedings on life sciences, medicine and pharmacology.
A Retrospective Study of Canine Pyometra in Segar Veterinary Hospital, Kuala Lumpur, Malaysia Year 2012-2016
Published date: Dec 03 2017
Journal Title: KnE Life Sciences
Issue title: The Veterinary Medicine International Conference (VMIC)
Pages: 153-165
Authors:
Abstract:
A retrospective study was used to analyse canine pyometra cases in Segar Veterinary Hospital, Kuala Lumpur, Malaysia from May 2012 to May 2016 and to investigate the relationship between pyometra and breed and age of dogs. The study was done through secondary collection of data from ambulatoirs of pyometra cases which were diagnosed based on anamnesis, examination of clinical signs and ultrasonography and/or radiography. The data collected includes breed categorised into small, medium, and large breeds, whereas the age are categorised into puppies, adulthood and geriatric. The data was then analysed with tree classification analysis and CATPCA (Principal Components Analysis for Categorical Data) analysis using SPSS program. A total of 80 cases of pyometra were recovered from female dog patients over the study period. Small breed dogs at 72.5% (n=58) and geriatric dogs at 62.5% (n=50) had the highest percentage of pyometra. The breeds Mongreal, German Shepard Dog, Mini Schnauzer, Silky Terrier, Toy Poodle, Beagle, Chow Chow, Golden Retriever, Rottweiler, Cocker Spaniel, White Terrier, Siberian Husky, and Pekingese aged older than 5.5 years had 100% from 37 cases of open-cervix pyometra. Geriatric and small breed dogs are inclined to have open-cervix pyometra. However adult and medium or large breed dogs have a higher possibility to have closed-cervix pyometra. These results serve to highlight the importance of public awareness regarding canine pyometra and further researches are needed to find out the effects of hormone therapy, frequency of births, and the bacteria present in uterus with pyometra.
Keywords: Canine pyometra, Open-cervix Pyometra, Closed-cervix Pyometra, Age and Breed
References:
Antonov, A.L., Atanasov, A.S., Fasulkov, I.R., Georgiev, P.I., Yotov, S., Karadaev, M. and Vasilev, N., 2015. Influence of some factors on the incidence of pyometra in the bitch. Bulgarian Journal of Veterinary Medicine, 18(4): 367-372.
Aqudelo, C.F. 2005. Cystic endometrial hyperplasia pyometra complex in cats. A review. The veterinary quarterly.
27(4): 173-182.
Arnold, S., I. Reichler and M. Hubler. 2006. Canine pyometra: new approaches to an old disease. World Congress WSAVA/FECAVA/CSAVA. 691-692.
Arora, N., Sandford, J., Browning, G.F., Sandy, J.R. and Wright, P.J., 2006. A model for cystic endometrial hyperplasia/pyometra complex in the bitch. Theriogenology, 66(6):1530-1536.
Bigliardi, E., Parmigiani, E., Cavirani, S., Luppi, A., Bonati, L. and Corradi, A., 2004. Ultrasonography and Cystic Hyperplasia–Pyometra Complex in the Bitch. Reproduction in Domestic Animals, 39: 136–140
Blendinger, K., 2007. Physiology and pathology of the estrous cycle of the bitch. In 56th Congresso Internazinale Multisala SCIVAC, Rimini. Proceedings of the 56th SCIVAC Congress 73-77.
Borresen, B. 1979. Pyometra in the dog—A pathophysiological investigation. II. Anamnestic, clinical and reproductive aspects. Nordic Vet. Med. 31: 251-257.
Borresen, B. 1980. Pyometra in the dog – a pathophysiological investigation. IV. Functional derangement of extragenital organs. Nordic Vet. Med. 32: 255-268.
Chastain, C.B., D. Panciera and C. Waters. 1999. Associations between age, parity, hormonal therapy and breed, and pyometra in Finnish dogs. Small Anim. Endocrinol. 9:8.
Concannon, P.W., Castracane, V.D., Temple, M. and Montanez, A., 2009. Endocrine control of ovarian function in dogs and other carnivores. Animal Reproduction, 6(1): 172-193.
Correa, J.E. 2002. Canine Breeding and Reproduction. Alabama A&M University. Alabama Cooperative Extension System.
De Bosschere, H., Ducatelle, R. and Tshamala, M., 2002. Is mechanically induced cystic endometrial hyperplasia (CEH) a suitable model for study of spontaneously occurring CEH in the uterus of the bitch. Reproduction in Domestic Animals, 37(3): 152-157.
Dominique, G., Josee and V. Jean-pierre. 2004. The Royal Canin Dog Encyclopedia. Aniwa S.A. French. Egenvall, A., Hagman, R., Bonnett, B.N., Hedhammar, A., Olson, P. and Lagerstedt, A.S., 2001. Breed risk of
pyometra in insured dogs in Sweden. Journal of veterinary internal medicine, 15(6): 530-538.
Ewald, B.H., 1961. A survey of the cystic hyperplasia–pyometra complex in the bitch. Small Anim Clin 1:383– 386.
Fakuda, S., 2001. Incidence of pyometra in colony raised beagle dogs. Exp. Anim. 50: 325-328.
Feldman, E.C. and Nelson, R.W., 2004a. Cystic endometrial hyperplasia/ pyometra complex. In: Kersey R, editor.
Canine and feline endocrinology and reproduction. WB Saunders Co. 852–867.
Feldman, E.C. and Nelson, R.W., 2004b. Ovarian Cycle and Vaginal Cytology. In: Kersey R, editor. Canine and Feline Endocrinology and Reproduction. WB Saunders Co. 526-546.
Foster R., 2016. Anatomy and Function of the Reproductive System in Dogs. Drs. Foster & Smith, Inc. Fransson, B., Lagerstedt, A.S., Hellmen, E. and Jonsson, P., 1997. Bacteriological findings, blood chemistry
profile and plasma endotoxin levels in bitches with pyometra or other uterine diseases. Journal of Veterinary Medicine Series A, 44(1‐10) (Abstr.): 417-426.
Fransson, B.A. and Ragle, C.A., 2003. Canine pyometra: an update on pathogenesis and treatment. Compendium,
25(08): 602-612.
Fukuda, S., 2001. Incidence of pyometra in colony-raised beagle dogs. Experimental animals, 50(4): 325-329. Gibson, A., R. Dean, D. Yates and J. Stavisky. 2013. Retrospective study of pyometra at five RSPCA hospitals in
the UK: 1728 cases from 2006 to 2011. Vet. Rec. 173(16): 396.
Gilbert, R.O., Nothling, J.O., Oettle, E.E. 1989. A retrospective study of 40 cases of canine pyometra-metritis treated with prostaglandin F-2 alpha and broad-spectrum antibacterial drugs. J Reprod Fertil Suppl 39:225–9.
Groppetti, D., Pecile, A., Arrighi, S., Di Giancamillo, A. and Cremonesi, F., 2010. Endometrial cytology and computerized morphometric analysis of epithelial nuclei: A useful tool for reproductive diagnosis in the bitch. Theriogenology, 73(7): 927-941.
Grundy, S.A., E. Feldman and A. Davidson. 2002. Evaluation of infertility in the bitch. Clin. Tech. Small Anim.
Pract. 17: 108-115.
Hagman, R., Kindahl, H., Fransson, B.A., Bergström, A., Holst, B.S. and Lagerstedt, A.S., 2006. Differentiation between pyometra and cystic endometrial hyperplasia/mucometra in bitches by prostaglandin F 2α metabolite analysis. Theriogenology, 66(2): 198-206.
Hagman, R., Lagerstedt, A.S., Hedhammar, Å. and Egenvall, A., 2011. A breed-matched case-control study of potential risk-factors for canine pyometra. Theriogenology, 75(7): 1251-1257.
Hardy, R.M., and Osborne, C.A. 1974. Canine pyometra: pathogenesis, physiology, diagnosis and treatment of uterine and extra-uterine lesions. J Am Anim Hosp Assoc. 10:245–68.
Hatmosrojo, R. and N.S. Budiana, 2008. Melatih Anjing Penjaga. Penebar Swadaya. Jakarta.
Jitpean, S., R. Hagman, B. Strom-Holst, O.V. Hoglund and A. Egenvall. 2012. Breed variance in the occurrence of pyometra and mammary tumours in Sweedish dogs. Dept. Clin. Sci. Fac. Vet. Med. Swed. Univ. Agric. Sci. SE-750 07 Uppsala. Sweden.
Jitpean, S., Ambrosen, A., Emanuelson, U. and Hagman, R., 2017. Closed cervix is associated with more severe illness in dogs with pyometra. BMC Veterinary Research, 13(1): 11.
Johnston, S.D., Kustritz, M.V.R., Olson, P.N.S. 2001. Disorders of the canine uterus and uterine tubes (oviducts).
In: Kersey R, editor. Canine and feline theriogenology. WB Saunders Co. 206–24.
Kahn, C.M. and S. Line. 2005. The Merck Veterinary Manual. 9th ed. Merck & Co. Inc. USA.
Kaymaz, M., Baştan, A., Erünal, N., Aslan, S. and Findik, M., 1999. The use of laboratory findings in the diagnosis of CEH-pyometra complex in the bitch. Turkish Journal of Veterinary and Animal Sciences, 23(2): 127-134.
Kempisty, B., Bukowska, D., Wozna, M., Piotrowska, H., Jackowska, M., Zuraw, A., Ciesiolka, S., Antosik, P., Maryniak, H., Ociepa, E. and Porowski, S., 2013. Endometritis and pyometra in bitches: a review. Vet Med, 58(6): 289-297.
Kustritz, M.V.R., 2011. Clinical canine and feline reproduction: evidence-based answers. John Wiley & Sons, 149-153.
Kutzler, M.A., Krekeler, N. and Hollinshead, F. 2014. Pyometra. Small Animal Soft Tissue Surgery, 623-634. Meyers Wallen M.H., Goldschmidt Flickinger, G.L. 1986. Prostaglandin F2a treatment of canine pyometra. J Am
Vet Med Assoc. 189:1557–1561.
Miklósi, Á., Kubinyi, E., Topál, J., Gácsi, M., Virányi, Z. and Csányi, V., 2003. A simple reason for a big difference: wolves do not look back at humans, but dogs do. Current Biology, 13(9): 763-766.
Miller, M.E., 1993. Anatomy of the Dog. W.B. Sounder Company. Philadelphia, 386-396.
Mylonakis, M.E., Koutinas, A.F., Baneth, G., Polizopoulou, Z., Yabsley, M.J., Varela, A.S., Tato, C.M., Dugan, V.G., Stalknecht, D.E., Little, S.E. and Davidson, W.R., 2014. Closed Cervix Pyometra in Canines. Indian Vet. J, 91(09): 78-80.
Nagasawa, M., Mogi, K. and Kikusui, T., 2009. Attachment between humans and dogs. Japanese Psychological Research, 51(3): 209-221.
Noakes, D., Parkinson, T.J., England, G.C. and Arthur, G.H., 2001. Arthur's veterinary reproduction and obstetrics.
WB Saunders. 33-37, 650-655.
Olsen S. J. and Olsen J. W., 1977. The Chinese Wolf, Ancestor of New World Dogs. Science 197(4303): 533-535.
Pretzer, S.D., 2008a. Abnormalities of the Canine Estrous Cycle: A review. Article presented at the Canine Breeder’s Symposium, St. Louis, Missouri 41-49
Pretzer, S.D., 2008b. Clinical presentation of canine pyometra and mucometra: a review. Theriogenology, 70(3):
359-363.
Ramsingh, L., Rao, K.S. and Muralimohan, K., 2013. Clinical Management of Pyometra in Bitches. IOSR Journal of Pharmacy, 3(1): 13-14.
Royalcanin.com.au, (2017). Dog Food by Size: Give Your Dog the Best. http://www.royalcanin.com.au/puppy-dog/dogs/size-based-nutrition. [12 January 2017]
Rynearson, E.K., 1978. Humans and pets and attachment. The British Journal of Psychiatry, 133(6): 550-555.
Sandholm, M., H. Vasenius and A.K. Kivisto. 1975. Pathogenesis of canine pyometra . JAVMA. 167: 1006-1010.
Savolainen, P., Zhang, Y.P., Luo, J., Lundeberg, J. and Leitner, T., 2002. Genetic evidence for an East Asian origin
of domestic dogs. Science, 298(5598): 1610-1613.
Smith, B.J. and S. Mangkoewidjojo. 1988. Pemeliharaan, Pembiakan dan Penggunaan Hewan Cobaan di daerah Tropis. Universitas Indonesia Press. Jakarta.
Smith, F.O. 2006. Canine Pyometra. Theriogenology. 66: 610-612.
Stone, E.A., M.P. Littman, J.L. Robertson and K.C. Bovee. 1988. Renal dysfunction in dogs with pyometra with the antigestagen aglepristione. J. Vet. Med., series A. 50: 375-379.
Thrusfield, M., 2013. Veterinary epidemiology. Elsevier. 31-36.
Udell, M.A. and Wynne, C.D., 2008. A Review of Domestic Dogs' (Canis Familiaris) Human‐Like Behaviors: Or Why Behavior Analysts Should Stop Worrying And Love Their Dogs. Journal of the experimental analysis of behavior, 89(2): 247-261.
Verstegen, J., Dhaliwal, G. and Verstegen-Onclin, K., 2008. Mucometra, cystic endometrial hyperplasia, and pyometra in the bitch: advances in treatment and assessment of future reproductive success. Theriogenology, 70(3): 364-374.
Vilà, C., Savolainen, P., Maldonado, J.E., Amorim, I.R., Rice, J.E., Honeycutt, R.L., Crandall, K.A., Lundeberg, J. and Wayne, R.K., 1997. Multiple and ancient origins of the domestic dog. Science, 276(5319): 1687-1689.
Wheaton, L.G., Johnson, A.L., Parker, A.J., Kneller, S.K. 1989. Results and complications of surgical treatment of pyometra: a review of 80 cases. J Am Anim Hosp Assoc 25:563–8.