Published date: Dec 03 2017

Journal Title: KnE Life Sciences

Issue title: The Veterinary Medicine International Conference (VMIC)

Pages: 77-83

DOI: 10.18502/kls.v3i6.1117

Lucia Tri Suwantitswant@gmail.comDepartment of Parasitology, Faculty of Veterinary Medicine, Universitas Airlangga Reseacher of Institute of Tropical Diseases, Universitas Airlangga

Mufasirin MufasirinDepartment of Parasitology, Faculty of Veterinary Medicine, Universitas Airlangga Reseacher of Institute of Tropical Diseases, Universitas Airlangga

Hani PlumeriastutiDepartment of Pathology, Faculty of Veterinary Medicine, Universitas Airlangga

Toxoplasma gondii infection in pregnant women cause defects in the newborn, such as hydrocephalus and eye damaged, even blindness. Histologically damage due to congenital infection of T. gondii need to be examined. Twenty pregnant mice were divided into two groups which are the treatment group and the control group. Each mouse in treatment group was infected with 10 takizoit by intraperitoneal. Each of the newborn were sacrified, their head were taken and their eye tissue were fixed in 10% of buffered formalin and the histological sample were made in HE and TUNEL staining. The result showed that the retina of the eye of the newborn from infected mice damage. The damages include: hemorrhage, infected retinal cells, eye growth inhibition and decreased of apoptosis index of the retina cells. 

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