KnE Engineering

ISSN: 2518-6841

The latest conference proceedings on all fields of engineering.

Methods and applications of label-free cell-based systems

Published date: Sep 05 2016

Journal Title: KnE Engineering

Issue title: Conference on Science and Engineering for Instrumentation, Environment and Renewable Energy

Pages:

DOI: 10.18502/keg.v1i1.493

Authors:

Joachim Wiest - wiest@cellasys.com

Abstract:
Label-free monitoring of living cells is used in various applications such as drug development, toxicology, regenerative medicine or environmental monitoring. The most prominent methods for monitoring the extracellular acidification, oxygen consumption, electrophysiological activity and morphological changes of living cells are described. Furthermore, the intelligent mobile lab (IMOLA) – a computer controlled system integrating cell monitoring and automated cell cultivation – is described as an example of a cell-based system for microphysiometry. Results from experiments in the field of environmental monitoring using algae are presented. An outlook toward the development of an organ-on-chip technology is given.
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