KnE Engineering

ISSN: 2518-6841

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A New Approach for Split Renal Function Assessment Based on 3D-Models Generated from Contrast-enhanced Multi-slice Computed Tomography (Msct) Scans and Mathematical Analysis: A Pilot Study

Published date:May 07 2018

Journal Title: KnE Engineering

Issue title: Russian Forum of Young Scientists (RFYS)

Pages:19–29

DOI: 10.18502/keg.v3i4.2221

Authors:
Abstract:

Introduction: Instrumental methods of examination may alter the course of treatment and patients’ management: from minimally invasive nephron-sparing procedures to radical operations. Objective:to present preliminary data on split kidney function assessment (in a kidney volume, e.g. segment) in patients with urological diseases.
Materials and methods: A prospective study was launched in aResearch Institute for Uronephrology and Reproductive Health from November, 2015 to February, 2017. 31 patients were enrolled into the study: 15 with stone kidney disease, 2 with kidney anomalies, 14 with renal tumors. Contrast-enhanced CT with 3D-models and
mathematical analysis were performed in all patients. Correlation between CT-based and renal scintigraphy-based measures of split renal function was estimated.

Results: CT-based methods for the calculation of split renal function with 3D-models showed correlation with renal scintigraphy (p<0.004, ttest). Conclusion: A new approach for split kidney function assessment based on contrast-enhanced CT with 3D-models and mathematical analysis allows for both acquiring detailed data on clinical anatomy and evaluation of renal function to promote preoperative decision-making.

References:

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[2] Lin K-J, Huang J-Y and Chen Y-S 2011 Fully Automatic Region of Interest Selection in Glomerular Filtration Rate Estimation from 99mTc-DTPA Renogram Journal of Digital Imaging24(6) 1010-23


[3] Fiev D N 2015 Virtual modelling for preoperative decision-making in kidney deseases(Moscow) pp 3-42


[4] Wesolowski C A, Wanasundara S N, Wesolowski M J, Erbas B and Babyn P S Eur2016 J Nucl Med Mol Imaging 43: 550.


[5] Nilsson H., Wadström J., Andersson L.‐G., Raland H. and Magnusson A. Measuring split renal function in renal donors: can computed tomography replace renography? Acta Radiologica 45-4, pp. 474 – 480


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