KnE Engineering

ISSN: 2518-6841

The latest conference proceedings on all fields of engineering.

RBE of "Prometeus" Facility Protons for Irradiation of Tumor Cells in vitro with One and Three Fields

Published date:Feb 21 2018

Journal Title: KnE Engineering

Issue title: XIII International Youth Scientific and Practical Conference "FUTURE OF ATOMIC ENERGY - AtomFuture 2017"

Pages:309-316

DOI: 10.18502/keg.v3i3.1630

Authors:
Abstract:

The study was aimed to the biological effectiveness of the proton scanning beam of the first Russian medical facility. The clonogenic assay of B-16 tumor cells was used as a test system. Cell irradiation was carried out in a suspension condition in a water phantom. Single and three-field exposures were studied. The dose interval was 2-8 Gy. The energy range from 47.5 to 92.0 MeV was used for the Bragg peak formation. The relative biological effectiveness of protons comparing to gamma-rays was 1.2 for single-field and 1.5 for three-field irradiation. The results obtained agree with literature data related to the used cell culture (B-16) and linear energy transfer range (3÷8 keV/µm).

References:

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