Published date: Feb 21 2018

Journal Title: KnE Engineering

Issue title: XIII International Youth Scientific and Practical Conference "FUTURE OF ATOMIC ENERGY - AtomFuture 2017"

Pages: 309-316

DOI: 10.18502/keg.v3i3.1630

Nasedkina N.V.

Beketov E.E.

Isaeva E.V.

Malakhov E.P.

Golovanova O.Y.

Ulyanenko L.N.

Chernukha A.E.

Saburov V.O.

Lepilina O.G.

Ulyanenko S.Е.

The study was aimed to the biological effectiveness of the proton scanning beam of the first Russian medical facility. The clonogenic assay of B-16 tumor cells was used as a test system. Cell irradiation was carried out in a suspension condition in a water phantom. Single and three-field exposures were studied. The dose interval was 2-8 Gy. The energy range from 47.5 to 92.0 MeV was used for the Bragg peak formation. The relative biological effectiveness of protons comparing to gamma-rays was 1.2 for single-field and 1.5 for three-field irradiation. The results obtained agree with literature data related to the used cell culture (B-16) and linear energy transfer range (3÷8 keV/µm).

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