Published date: Apr 17 2018

Journal Title: KnE Energy

Issue title: The 2nd International Symposium "Physics, Engineering and Technologies for Biomedicine"

Pages: 486–492

DOI: 10.18502/ken.v3i2.1855

A V Tcibulnikovamemorgold@mail.ru

I A Degterev

V V Brykhanov

N A Myslitskaya

I G Samusev

In this work, the spectral study of aqueous extract of Curcuma Longa (Turmeric) to determine the photodynamic properties. It is established that due to the absorption extract light of wavelength 400-450 nm and intensive fluorescence in the red region of the spectrum, this extract can be used as a sensitizer of singlet oxygen (1Δ

[1] Z. Huang, “A review of progress in clinical photodynamic therapy,” Technol. Cancer Res. Treat, vol. 4 (3): 283–93, 2005.


[2] V. Monge-Fuentes, L.A. Muehlmann, J.P. Figueiro Longo, J.R. Silva, M.L. Fascineli, P. de Souza, F. Faria, I.A. Degterev and others, “Photodynamic therapy mediated by acai oil (Euterpe oleracea Martius) in nanoemulsion: A potential treatment for melanoma,” Journal of Photochemistry & Photobiology, B:Biology, vol. 166, pp. 301- 310, 2017.


[3] X.F.Zhang, X. Yang, “Singlet oxygen generation and triplet excited-state spectra of brominated BODIPY,” The Journal of Physical Chemistry. B, vol. 117(18), pp. 5533- 5539, 2013.


[4] S. Clement, M. Sobhan, W. Deng, E. Camilleri, E.M. Goldys, “Nanoparticle-mediated singlet oxygen generation from photosensitizers, ” Journal of Photochemistry and Photobiology A: Chemistry, vol. 332, no.1, pp. 66-71, 2017.


[5] M. Riethmüller, N. Burger N, G. Bauer, “Singlet oxygen treatment of tumor cells triggers extracellular singlet oxygen generation, catalase inactivation and reactivation of intercellular apoptosis-inducing signaling,” Redox Biol, pp.57-68, 2017.


[6] Huaiyi Huang, Pingyu Zhang, Bole Yu and others “Synthesis, characterization and biological evaluation of mixed-ligand ruthenium(II) complexes for photodynamic therapy,” Dalton Transactions, vol. 44, no. 39, pp. 17335-17345, 2015.


[7] I.S. Vinklarek, M. Scholz, R. Dedic, J. Hala “Singlet oxygen feedback delayed fluorescence of protoporphyrin IX in organic solutions,” Photochem. Photobiol. Sci.,vol.16, no. 4, pp. 507-518, 2017.


[8] M. Scholz, R. Ddic, T. Breitenbach and J.Hála “Singlet oxygen-sensitized delayed fluorescence of common watersoluble Photosensitizers,” Photochem. Photobiol. Sci., vol. 12, no. 10, pp. 1873-1884, 2013.


[9] Jiangping Liu, Yu Chen, Guanying Li and others, “Ruthenium(II) polypyridyl complexes as mitochondria-targeted two-photon photodynamic anticancer agents,” Biomaterials vol. 56, pp. 140-153, 2015.


[10] Yao Liu1, Rong Qin1, Sebastian A. J. Zaat, Eefjan Breukink, Michal Heger, “Antibacterial photodynamic therapy: overview of a promising approach to fight antibioticresistant bacterial infections,” Journal of Clinical and Translational Research, vol.1, no.3, pp. 140-167, 2015.


[11] B.B. Aggarwal, K.B. Harikumar, “Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases,”Int J Biochem Cell Biol, vol. 41, no. 1, pp.40-59, 2009.


[12] Kate C. Blanco, Natalia M. Inada, Fernanda M. Carbinatto and Vanderlei S. Bagnato, “Antimicrobial Efficacy of Curcumin Formulations by Photodynamic Therapy, “Journal of Pharmacy and Pharmacology, vol. 5, pp. 506-511, 2017.


[13] M.C.Rodrigues, L.A.Muehlmann, P.F. João, J.P.F.Longo, R.C.Silva, I.B.Graebner, I.A.Degterev, C.M. Lucci, R.B.Azevedo, M.P. Garcia, “Photodynamic Therapy Based on Arrabidaea chica (Craj-iru) Extract Nanoemulsion: In vitro Activity against Monolayers and Spheroids of Human Mammary Adenocarcinoma MCF-7 Cells, “J. Nanomed. Nanotechnol, vol. 6, pp. 286 – 291, 2015.


[14] Skehan, P., Storeng, R., Scudiero, D., Monks, A., J. McMahon., D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, M.R. Boyd, “New Colori-metric Cytotoxicity Assay for Anticancer-Drug Screening,” Journal of the National Cancer Institute, vol. 82, Issue 13, pp. 1107–1112, 1990.